ArticleProceedings of the National Academy of Sciences of the United States of America2018
Suppression of frontal eye field neuronal responses with maintained fixation.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Fixation Task: A Simple Eye Movement Task Reveals an Impairment in Schizophrenia.Schizophrenia bulletin · 2026Article
- Role of neuronal oscillations in memory driven visual processing.BMC biology · 2026Article
- Orchestration of saccadic eye-movements by brain rhythms in macaque Frontal Eye Field.Scientific reports · 2023Article
- Oculomotor changes following learned use of an eccentric retinal locus.Vision research · 2022Article
- Developmental maturation of causal signaling hubs in voluntary control of saccades and their functional controllability.Cerebral cortex (New York, N.Y. : 1991) · 2022Article
- The roles of the lateral intraparietal area and frontal eye field in guiding eye movements in free viewing search behavior.Journal of neurophysiology · 2021Article
- Responses to Visual Speech in Human Posterior Superior Temporal Gyrus Examined with iEEG Deconvolution.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020Article
- The functional roles of neural remapping in cortex.Journal of vision · 2020Article
- The neural instantiation of a priority map.Current opinion in psychology · 2019Review
- Synchronization between frontal eye field and area V4 during free-gaze visual search.Zoological research · 2019Article
- Motor cost affects the decision of when to shift gaze for guiding movement.Journal of neurophysiology · 2019Article
- Neurons in FEF Keep Track of Items That Have Been Previously Fixated in Free Viewing Visual Search.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2019Article
- Selective Influence and Sequential Operations: A Research Strategy for Visual Search.Visual cognition · 2019Article
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Authors and funding
3 authors.
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Abstract
The decision of where to make an eye movement is thought to be driven primarily by responses to stimuli in neurons' receptive fields (RFs) in oculomotor areas, including the frontal eye field (FEF) of prefrontal cortex. It is also thought that a saccade may be generated when the accumulation of this activity in favor of one location or another reaches a threshold. However, in the reading and scene perception fields, it is well known that the properties of the stimulus at the fovea often affect when the eyes leave that stimulus. We propose that if FEF plays a role in generating eye movements, then the identity of the stimulus at fixation should affect the FEF responses so as to reduce the probability of making a saccade when fixating an item of interest. Using a visual foraging task in which animals could make multiple eye movements within a single trial, we found that responses were strongly modulated by the identity of the stimulus at the fovea. Specifically, responses to the stimulus in the RF were suppressed when the animal maintained fixation for longer durations on a stimulus that could be associated with a reward. We suggest that this suppression, which was predicted by models of eye movement behavior, could be a mechanism by which FEF can modulate the temporal flow of saccades based on the importance of the stimulus at the fovea.
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