Evidence map›Paper›PMID 29311274›Full record

ArticleJournal of bacteriology2018

Mutations in Escherichia coli Polyphosphate Kinase That Lead to Dramatically Increased

Amanda K Rudat, Arya Pokhrel, Todd J Green, Michael J Gray

Abstract read
In one paragraph

Article in Journal of bacteriology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed.

  1. Article
  2. The roles and synthesis of inorganic polyphosphate inbioRxiv : the preprint server for biology · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. The Protein Scaffolding Functions of Polyphosphate.Journal of molecular biology · 2024
    Review
  10. Article
  11. The role of metals in hypothiocyanite resistance inbioRxiv : the preprint server for biology · 2024
    Article
  12. Article
  13. Article
  14. Article
  15. Metabolic engineering ofEngineering microbiology · 2022
    Review
  16. Article
  17. Review
  18. Review
  19. Article
  20. Transcriptional Responses ofFrontiers in microbiology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Amanda K RudatDepartment of Microbiology, School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Arya PokhrelDepartment of Microbiology, School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Todd J GreenDepartment of Microbiology, School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Michael J GrayDepartment of Microbiology, School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA mjgray@uab.edu.ORCID https://orcid.org/0000-0002-7112-4188

Funding

Molecular Mechanisms of Bacterial Stress Response Relevant to Host-Microbe InteractionsR35GM124590 · NIGMS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Michael Jeffrey Gray · 2017 to 2026
$3.5M
NIGMS NIH HHS R35 GM124590
6 · The paper itself

Abstract

Bacteria synthesize inorganic polyphosphate (polyP) in response to a wide variety of stresses, and production of polyP is essential for stress response and survival in many important pathogens and bacteria used in biotechnological processes. However, surprisingly little is known about the molecular mechanisms that control polyP synthesis. We have therefore developed a novel genetic screen that specifically links growth of

Indexed as

MutationEscherichia coliMagnesiumPhosphotransferases (Phosphate Group Acceptor)PolyphosphatesStress, PhysiologicalMagnesiumPhosphotransferases (Phosphate Group Acceptor)polyphosphate kinasePolyphosphatesbacterial geneticsenzyme engineeringinorganic polyphosphatemutagenesisstress response

Identifiers

PMID29311274
PMCPMC5826030

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.