Evidence map›Paper›PMID 29311245›Full record

ArticleInfection and immunity2018

Both Major Histocompatibility Complex Class I (MHC-I) and MHC-II Molecules Are Required, while MHC-I Appears To Play a Critical Role in Host Defense against Primary Coxiella burnetii Infection.

Laura Buttrum, Lindsey Ledbetter, Rama Cherla, Yan Zhang, William J Mitchell, Guoquan Zhang

Open access · bronzeAbstract read
In one paragraph

Article in Infection and immunity, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.0field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 26 citations in OpenAlex.

  1. Trial
  2. Review
  3. Review
  4. Article
  5. Frontiers in immunology · 2024
    Article
  6. Review
  7. Review
  8. Cytometry profiling ofFrontiers in immunology · 2023
    Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. PromiscuousFrontiers in immunology · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Laura ButtrumDepartment of Veterinary Pathobiology, College of Veterinary Medicine, University of Missouri-Columbia, Columbia, Missouri, USA.
Lindsey LedbetterDepartment of Veterinary Pathobiology, College of Veterinary Medicine, University of Missouri-Columbia, Columbia, Missouri, USA.
Rama CherlaDepartment of Veterinary Pathobiology, College of Veterinary Medicine, University of Missouri-Columbia, Columbia, Missouri, USA.
Yan ZhangDepartment of Veterinary Pathobiology, College of Veterinary Medicine, University of Missouri-Columbia, Columbia, Missouri, USA.
William J MitchellDepartment of Veterinary Pathobiology, College of Veterinary Medicine, University of Missouri-Columbia, Columbia, Missouri, USA.
Guoquan ZhangDepartment of Veterinary Pathobiology, College of Veterinary Medicine, University of Missouri-Columbia, Columbia, Missouri, USA zhangguo@missouri.edu.
University of Missouri · USMissouri College · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To understand the role of class I major histocompatibility complex (MHC-I) and class II MHC (MHC-II) antigen presentation pathways in host defense against

Indexed as

AnimalsAntigens, BacterialATP Binding Cassette Transporter, Subfamily B, Member 2CD8-Positive T-LymphocytesCoxiella burnetiiDisease Models, AnimalDisease ResistanceFemaleGranzymesHistocompatibility Antigens Class IHistocompatibility Antigens Class IIHost-Pathogen InteractionsInterferon-gammaMiceMice, KnockoutQ FeverAntigens, BacterialATP Binding Cassette Transporter, Subfamily B, Member 2GranzymesHistocompatibility Antigens Class IHistocompatibility Antigens Class IIInterferon-gammaTap1 protein, mouseantigen presentationCoxiella burnetiiCTLgranzymeimmune responseMHC-IMHC-IIperforinTAP

Identifiers

PMID29311245
PMCPMC5865044
OpenAlexW2783961803

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.