Evidence map›Paper›PMID 29311240›Full record

ArticleInfection and immunity2018

Potential Immunological Biomarkers for Detection of Mycobacterium tuberculosis Infection in a Setting Where M. tuberculosis Is Endemic, Ethiopia.

Takele Teklu, Keehwan Kwon, Biniam Wondale, Milkessa HaileMariam, Aboma Zewude, Girmay Medhin, Mengistu Legesse, Rembert Pieper, Gobena Ameni

Open access · bronzeAbstract read
In one paragraph

Article in Infection and immunity, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Takele TekluAklilu Lemma Institute of Pathobiology, Addis Ababa University, Addis Ababa, Ethiopia takeleteklua@gmail.com.
Keehwan KwonJ. Craig Venter Institute, Rockville, Maryland, USA.
Biniam WondaleAklilu Lemma Institute of Pathobiology, Addis Ababa University, Addis Ababa, Ethiopia.
Milkessa HaileMariamAklilu Lemma Institute of Pathobiology, Addis Ababa University, Addis Ababa, Ethiopia.
Aboma ZewudeAklilu Lemma Institute of Pathobiology, Addis Ababa University, Addis Ababa, Ethiopia.
Girmay MedhinAklilu Lemma Institute of Pathobiology, Addis Ababa University, Addis Ababa, Ethiopia.
Mengistu LegesseAklilu Lemma Institute of Pathobiology, Addis Ababa University, Addis Ababa, Ethiopia.
Rembert PieperJ. Craig Venter Institute, Rockville, Maryland, USA.
Gobena AmeniAklilu Lemma Institute of Pathobiology, Addis Ababa University, Addis Ababa, Ethiopia.
Addis Ababa University · ETJ. Craig Venter Institute · USAmbo University · ETArba Minch University · ETUniversity of Gondar · ET

Funding

Ethiopia-Emory TB Research Training ProgramD43TW009127 · FIC · EMORY UNIVERSITY · PI HENRY M BLUMBERG, Kidist Bobosha · 2013 to 2026
$3.4M
Systems Biology for Molecular Analysis of Tuberculosis in EthiopiaU01HG007472 · NHGRI · ADDIS ABABA UNIVERSITY · PI AMENI, GOBENA · 2013 to 2016
$1.2M
FIC NIH HHS D43 TW009127NHGRI NIH HHS U01 HG007472
6 · The paper itself

Abstract

Accurate diagnosis and early treatment of tuberculosis (TB) and latent TB infection (LTBI) are vital to prevent and control TB. The lack of specific biomarkers hinders these efforts. This study's purpose was to screen immunological markers that discriminate

Indexed as

AdultBiomarkersCase-Control StudiesCytokinesEthiopiaFemaleHumansMaleMiddle AgedMycobacterium tuberculosisROC CurveTuberculosisYoung AdultBiomarkersCytokinescytokine arrayEthiopiaIL-17immunological markerMycobacteriumRANTEStuberculosis

Identifiers

PMID29311240
PMCPMC5865051
OpenAlexW2791006692

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.