Evidence map›Paper›PMID 29311236›Full record

ArticleInfection and immunity2018

Detrimental Influence of Alveolar Macrophages on Protective Humoral Immunity during Francisella tularensis SchuS4 Pulmonary Infection.

Donald J Steiner, Yoichi Furuya, Dennis W Metzger

Open access · bronzeAbstract read
In one paragraph

Article in Infection and immunity, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Host Immunity andMicroorganisms · 2021
    Review
  3. Microorganisms · 2021
    Review
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Donald J SteinerDepartment of Immunology and Microbial Disease, Albany Medical College, Albany, New York, USA.
Yoichi FuruyaDepartment of Immunology and Microbial Disease, Albany Medical College, Albany, New York, USA.
Dennis W MetzgerDepartment of Immunology and Microbial Disease, Albany Medical College, Albany, New York, USA metzged@mail.amc.edu.
Albany Medical Center Hospital · US

Funding

TLR2/NLR Signal Regulation of Protective Immunity to F. TularensisP01AI056320 · NIAID · ALBANY MEDICAL COLLEGE · PI METZGER, DENNIS W · 2003 to 2016
$22.9M
NIAID NIH HHS P01 AI056320
6 · The paper itself

Abstract

Opsonizing antibody is a critical component of the host protective immune response against many respiratory pathogens. However, the role of antibodies in protection against pulmonary infection with highly virulent

Indexed as

Immunity, HumoralAnimalsAntibodies, BacterialFrancisella tularensisMacrophages, AlveolarMiceNeutrophilsPneumoniaRespiratory BurstSepsisTularemiaAntibodies, BacterialFrancisella tularensishumoral immunitylung infectionmacrophages

Identifiers

PMID29311236
PMCPMC5865038
OpenAlexW2783297064

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.