ArticleGenetics2018
Estimating Barriers to Gene Flow from Distorted Isolation-by-Distance Patterns.
Article in Genetics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 50 citations in OpenAlex.
- Shaping of developmental gradients through selection on multiple loci inScience advances · 2026Article
- Genome-wide cline analysis identifies new locus contributing to a barrier to gene flow across an Antirrhinum hybrid zone.PLoS genetics · 2026Article
- Genealogical Analysis of Replicate Flower Colour Hybrid Zones in Antirrhinum.Molecular ecology · 2025Article
- The effect of habitat loss and fragmentation on isolation by distance and divergence.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- A Landscape Genetics Approach Reveals Species-Specific Connectivity Patterns for Stream Insects in Fragmented Habitats.Ecology and evolution · 2025Article
- Insights into the genetic diversity and species distribution of Oswaldocruzia nematodes (Trichostrongylida: Molineidae) in Europe: apparent absence of geographic and population structuring in amphibians.Parasite (Paris, France) · 2025Article
- A spatial approach to jointly estimate Wright's neighborhood size and long-term effective population size.Genetics · 2024Article
- Limited genetic variability and spatial population structure in grasshoppers between natural and metal-contaminated areas in Egypt.Journal of insect science (Online) · 2024Article
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- Effects of fine-scale population structure on the distribution of heterozygosity in a long-term study of Antirrhinum majus.Genetics · 2022Article
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- Wild snapdragon plant pedigree sheds light on limited connectivity enhanced by higher migrant reproductive success in a fragmented landscape.Open research Europe · 2021Article
- Potential adaptive divergence between subspecies and populations of snapdragon plants inferred from QMolecular ecology · 2020Article
- Detecting geospatial patterns of Plasmodium falciparum parasite migration in Cambodia using optimized estimated effective migration surfaces.International journal of health geographics · 2020Article
- Genetic Landscapes Reveal How Human Genetic Diversity Aligns with Geography.Molecular biology and evolution · 2020Article
- Testing the Effect of Mountain Ranges as a Physical Barrier to Current Gene Flow and Environmentally Dependent Adaptive Divergence inFrontiers in genetics · 2019Article
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- Can secondary contact following range expansion be distinguished from barriers to gene flow?PeerJ · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In continuous populations with local migration, nearby pairs of individuals have on average more similar genotypes than geographically well-separated pairs. A barrier to gene flow distorts this classical pattern of isolation by distance. Genetic similarity is decreased for sample pairs on different sides of the barrier and increased for pairs on the same side near the barrier. Here, we introduce an inference scheme that uses this signal to detect and estimate the strength of a linear barrier to gene flow in two dimensions. We use a diffusion approximation to model the effects of a barrier on the geographic spread of ancestry backward in time. This approach allows us to calculate the chance of recent coalescence and probability of identity by descent. We introduce an inference scheme that fits these theoretical results to the geographic covariance structure of bialleleic genetic markers. It can estimate the strength of the barrier as well as several demographic parameters. We investigate the power of our inference scheme to detect barriers by applying it to a wide range of simulated data. We also showcase an example application to an
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.