ArticleClinical cancer research : an official journal of the American Association for Cancer Research2018
Expanded Genomic Profiling of Circulating Tumor Cells in Metastatic Breast Cancer Patients to Assess Biomarker Status and Biology Over Time (CALGB 40502 and CALGB 40503, Alliance).
Open access · bronzeAbstract read
In one paragraph
Article in Clinical cancer research : an official journal of the American Association for Cancer Research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
2.3field-weighted citation impact, top 9% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 45 citations in OpenAlex.
- Isolation and molecular analysis of circulating tumor cells from lung cancer patients using a microfluidic chip type cell sorter.Cancer science · 2018Trial
- A hormetic transcriptional program coregulates invasion, proliferation and dormancy to define metastatic potential.Nature communications · 2026Article
- SWIFT-seq enables comprehensive single-cell transcriptomic profiling of circulating tumor cells in multiple myeloma and its precursors.Nature cancer · 2025Article
- Single-cell multi-omics in cancer immunotherapy: from tumor heterogeneity to personalized precision treatment.Molecular cancer · 2025Review
- Antitumor CD4+ T Helper 1 Cells Target and Control the Outgrowth of Disseminated Cancer Cells.Cancer immunology research · 2025Article
- Inspiring a convergent engineering approach to measure and model the tissue microenvironment.Heliyon · 2024Review
- Advances in the role of circulating tumor cell heterogeneity in metastatic small cell lung cancer.Cancer innovation · 2024Review
- Research progress on the multi-omics and survival status of circulating tumor cells.Clinical and experimental medicine · 2024Review
- Transitioning single-cell genomics into the clinic.Nature reviews. Genetics · 2023Review
- Advances in novel strategies for isolation, characterization, and analysis of CTCs and ctDNA.Therapeutic advances in medical oncology · 2023Review
- Signatures of Breast Cancer Progression in the Blood: What Could Be Learned from Circulating Tumor Cell Transcriptomes.Cancers · 2022Review
- Shallow WGS of individual CTCs identifies actionable targets for informing treatment decisions in metastatic breast cancer.British journal of cancer · 2022Article
- Correlation between targeted RNAseq signature of breast cancer CTCs and onset of bone-only metastases.British journal of cancer · 2022Article
- Prognostic Relevance of Estrogen Receptor Status in Circulating Tumor Cells in Breast Cancer Patients Treated With Endocrine Therapy.Frontiers in oncology · 2022Article
- An exploratory study on the checkout rate of circulating tumor cells and the prediction of efficacy of neoadjuvant therapy and prognosis in patients with HER-2-positive early breast cancer.Frontiers in oncology · 2022Article
- Circulating tumor cells: biology and clinical significance.Signal transduction and targeted therapy · 2021Review
- Serial Analysis of Circulating Tumor Cells in Metastatic Breast Cancer Receiving First-Line Chemotherapy.Journal of the National Cancer Institute · 2021Article
- Exploration of Circulating Tumour Cell (CTC) Biology: A Paradigm Shift in Liquid Biopsy.Indian journal of clinical biochemistry : IJCB · 2021Review
- Current Status of Circulating Tumor Cells, Circulating Tumor DNA, and Exosomes in Breast Cancer Liquid Biopsies.International journal of molecular sciences · 2020Review
- Analysis of the serial circulating tumor cell count during neoadjuvant chemotherapy in breast cancer patients.Scientific reports · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
16 authors at 2 institutions in 1 country.
Mark Jesus M MagbanuaDivision of Hematology/Oncology, University of California at San Francisco, San Francisco, California. mark.magbanua@ucsf.edu john.park@ucsf.edu.
Hope S RugoDivision of Hematology/Oncology, University of California at San Francisco, San Francisco, California.
Denise M WolfDepartment of Laboratory Medicine, University of California at San Francisco, San Francisco, California.
Louai HauraniehDivision of Hematology/Oncology, University of California at San Francisco, San Francisco, California.
Ritu RoyHelen Diller Family Comprehensive Cancer Center and Computational Biology and Informatics, University of California at San Francisco, San Francisco, California.
Praveen PendyalaDivision of Hematology/Oncology, University of California at San Francisco, San Francisco, California.
Eduardo V SosaDivision of Hematology/Oncology, University of California at San Francisco, San Francisco, California.
Janet H ScottDivision of Hematology/Oncology, University of California at San Francisco, San Francisco, California.
Jin Sun LeeDivision of Hematology/Oncology, University of California at San Francisco, San Francisco, California.
Brandelyn PitcherAlliance Statistics and Data Center, Duke University, Durham, North Carolina.
Terry HyslopAlliance Statistics and Data Center, Duke University, Durham, North Carolina.
William T BarryAlliance Statistics and Data Center, Dana-Farber Cancer Institute, Boston, Massachusetts.
Steven J IsakoffMassachusetts General Hospital Cancer Center, Boston, Massachusetts.
Maura DicklerMemorial Sloan Kettering Cancer Center, New York, New York.
Laura Van't VeerDepartment of Laboratory Medicine, University of California at San Francisco, San Francisco, California.
John W ParkDivision of Hematology/Oncology, University of California at San Francisco, San Francisco, California. mark.magbanua@ucsf.edu john.park@ucsf.edu.
Massachusetts General Hospital · USMemorial Sloan Kettering Cancer Center · US
Funding
X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4MTranslational InformaticsP30CA082103 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Jennifer Leigh Clarke · 1999 to 2026
$209.7MMember Site CoreU10CA180821 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI Evanthia Galanis · 2014 to 2026
$177.3MStatistics CoreU10CA180882 · NCI · MAYO CLINIC ROCHESTER · PI Sumithra Jay Mandrekar · 2014 to 2026
$115.0MNCTN Lead Academic Participating Site at Dana-Farber/Partners Cancer CareU10CA180867 · NCI · DANA-FARBER CANCER INST · PI BURSTEIN, HAROLD JOHN, KIBEL, ADAM S · 2014 to 2018
$6.2MNetwork Lead Academic Participating Site: Memorial Sloan-Kettering Cancer CenterU10CA180791 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI AGHAJANIAN, CAROL, MORRIS, MICHAEL J · 2014 to 2018
$4.6MCALGB Member Site: University of California - San FranciscoU10CA138561 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI RYAN, CHARLES JAMES · 2009 to 2012
$430kNCI NIH HHS P30 CA008748NCI NIH HHS P30 CA082103NCI NIH HHS U10 CA138561NCI NIH HHS U10 CA180791NCI NIH HHS U10 CA180821NCI NIH HHS U10 CA180867NCI NIH HHS U10 CA180882
Abstract
PubMed holds no abstract for this paper.
Indexed as
Biomarkers, TumorBreast NeoplasmsCell Line, TumorComparative Genomic HybridizationEpithelial Cell Adhesion MoleculeErb-b2 Receptor Tyrosine KinasesFemaleGene Expression ProfilingGenomicsHumansKaplan-Meier EstimateMCF-7 CellsNeoplasm MetastasisNeoplastic Cells, CirculatingSingle-Cell AnalysisBiomarkers, TumorEPCAM protein, humanEpithelial Cell Adhesion MoleculeERBB2 protein, humanErb-b2 Receptor Tyrosine Kinases
Identifiers
What OpenQuestion holds
Textmetadata
LicenceTDM
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.