Evidence map›Paper›PMID 29311073›Full record

ArticleAntimicrobial agents and chemotherapy2018

Validation of Cycloserine Efficacy in Treatment of Multidrug-Resistant and Extensively Drug-Resistant Tuberculosis in Beijing, China.

Xia Yu, Xiling Zeng, Wenhui Shi, Yanjie Hu, Wenjuan Nie, Naihui Chu, Hairong Huang

Open access · bronzeAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 17 citations in OpenAlex.

  1. Trial
  2. Article
  3. Therapeutic drug monitoring in tuberculosis.European journal of clinical pharmacology · 2024
    Review
  4. Article
  5. Article
  6. Article
  7. Anti-tuberculosis drug developmentFrontiers in microbiology · 2022
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Xia Yu *National Clinical Laboratory on Tuberculosis, Beijing Key Laboratory for Drug-Resistant Tuberculosis Research, Beijing Chest Hospital, Capital Medical University, Beijing Tuberculosis and Thoracic Tumor Institute, Beijing, China.
Xiling Zeng *Department of Tuberculosis, Beijing Chest Hospital, Capital Medical University, Beijing, China.
Wenhui ShiDepartment of Tuberculosis, Beijing Chest Hospital, Capital Medical University, Beijing, China.
Yanjie HuNational Clinical Laboratory on Tuberculosis, Beijing Key Laboratory for Drug-Resistant Tuberculosis Research, Beijing Chest Hospital, Capital Medical University, Beijing Tuberculosis and Thoracic Tumor Institute, Beijing, China.
Wenjuan NieDepartment of Tuberculosis, Beijing Chest Hospital, Capital Medical University, Beijing, China.
Naihui ChuDepartment of Tuberculosis, Beijing Chest Hospital, Capital Medical University, Beijing, China dongchu1994@sina.com huanghairong@tb123.org.
Hairong HuangNational Clinical Laboratory on Tuberculosis, Beijing Key Laboratory for Drug-Resistant Tuberculosis Research, Beijing Chest Hospital, Capital Medical University, Beijing Tuberculosis and Thoracic Tumor Institute, Beijing, China dongchu1994@sina.com huanghairong@tb123.org.
Capital Medical University · CNBeijing Chest Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cycloserine (Cs) is recommended by the World Health Organization as a second-line drug to treat multidrug-resistant tuberculosis (MDR-TB); however, its efficacy has never been sufficiently evaluated. To gain some insights into the value of cycloserine for MDR-TB treatment,

Indexed as

AdolescentAdultAntitubercular AgentsBeijingCycloserineFemaleHumansMaleMicrobial Sensitivity TestsMiddle AgedMycobacterium tuberculosisRisk FactorsTuberculosis, Multidrug-ResistantYoung AdultAntitubercular AgentsCycloserinecycloserineefficacyextensive drug resistancemultiple drug resistancetherapeutic drug monitoringtuberculosis

Identifiers

PMID29311073
PMCPMC5826102
OpenAlexW2782128623

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.