Evidence map›Paper›PMID 29311064›Full record

ArticleAntimicrobial agents and chemotherapy2018

High-Content Screening of the Medicines for Malaria Venture Pathogen Box for Plasmodium falciparum Digestive Vacuole-Disrupting Molecules Reveals Valuable Starting Points for Drug Discovery.

Jie Xin Tong, Rajesh Chandramohanadas, Kevin Shyong-Wei Tan

Open access · bronzeAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.9field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Chloroquine induces eryptosis inFrontiers in cellular and infection microbiology · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Methods Used to Investigate theFrontiers in cellular and infection microbiology · 2021
    Review
  12. Calcium in the Backstage of Malaria Parasite Biology.Frontiers in cellular and infection microbiology · 2021
    Review
  13. Article
  14. AntimalarialACS medicinal chemistry letters · 2020
    Article
  15. Drug design, development and therapy · 2020
    Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Jie Xin TongLaboratory of Molecular and Cellular Parasitology, Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Rajesh ChandramohanadasPillar of Engineering Product Development, Singapore University of Technology and Design, Singapore.ORCID 0000-0002-8760-0396
Kevin Shyong-Wei TanLaboratory of Molecular and Cellular Parasitology, Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore mictank@nus.edu.sg.ORCID 0000-0001-9022-729X
National University of Singapore · SGSingapore University of Technology and Design · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

High-Throughput Screening AssaysAniline CompoundsAntimalarialsCalciumChloroquineCrystallizationDatabases, PharmaceuticalDrug ResistanceErythrocytesFluorescent DyesHemeproteinsHumansIntracellular MembranesPermeabilityPlasmodium falciparumSmall Molecule LibrariesAniline CompoundsAntimalarialsCalciumChloroquineFluo 4Fluorescent DyesHemeproteinshemozoinSmall Molecule LibrariesXanthenescalcium sensorscell deathdigestive vacuolehigh-content screeningmalariaPathogen Box

Identifiers

PMID29311064
PMCPMC5826141
OpenAlexW2783418877

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.