Evidence map›Paper›PMID 29310768›Full record

ReviewThe journal of allergy and clinical immunology. In practice

SJS/TEN 2017: Building Multidisciplinary Networks to Drive Science and Translation.

Katie D White, Riichiro Abe, Michael Ardern-Jones, Thomas Beachkofsky, Charles Bouchard, Bruce Carleton, James Chodosh, Ricardo Cibotti, Robert Davis, Joshua C Denny and 34 more

Abstract readReview
In one paragraph

Review in The journal of allergy and clinical immunology. In practice. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 71 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
71citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

71 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Review
  6. Article
  7. Article
  8. Article
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  11. Review
  12. Challenges in Diagnosing and Treatment of Pediatric Necrotic Skin Conditions: A Retrospective Study.Medical science monitor : international medical journal of experimental and clinical research · 2025
    Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Drug hypersensitivity reactions: review of the state of the science for prediction and diagnosis.Toxicological sciences : an official journal of the Society of Toxicology · 2024
    Review
  18. Article
  19. Article
  20. Article

11 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

44 authors.

Katie D WhiteVanderbilt University Medical Center, Nashville, Tenn.
Riichiro AbeNiigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.
Michael Ardern-JonesUniversity of Southampton, Southampton, United Kingdom.
Thomas BeachkofskyWilford Hall Ambulatory Surgical Center, Lackland Air Force Base, San Antonio, Texas.
Charles BouchardLoyola University Medical Center, Chicago, Ill.
Bruce CarletonUniversity of British Columbia, Vancouver, British Columbia, Canada; B.C. Children's Hospital, British Columbia, Vancouver, British Columbia, Canada.
James ChodoshMassachusetts Eye and Ear, Harvard Medical School, Boston, Mass.
Ricardo CibottiNational Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, Md.
Robert DavisUniversity of Tennessee Health Sciences, Memphis, Tenn.
Joshua C DennyVanderbilt University Medical Center, Nashville, Tenn.
Roni P Dodiuk-GadEmek Medical Center, Technion-Institute of Technology, Afula, Israel; Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada.
Elizabeth N ErgenUniversity of Alabama at Birmingham, Birmingham, Ala.
Jennifer L GoldmanChildren's Mercy Hospital Kansas City, Kansas City, Mo.
James H HolmesWake Forest Baptist Medical Center, Winston-Salem, NC; Wake Forest University School of Medicine, Winston-Salem, NC.
Shuen-Iu HungNational Yang-Ming University, Taipei, Taiwan.
Mario E LacoutureMemorial Sloan Kettering Cancer Center, New York, NY.
Rannakoe J LehloenyaUniversity of Cape Town and Groote Schuur Hospital, Cape Town, South Africa.
Simon MallalVanderbilt University Medical Center, Nashville, Tenn; Institute for Immunology and Infectious Diseases, Murdoch University, Murdoch, Western Australia, Australia.
Teri A ManolioNational Human Genome Research Institute, National Institutes of Health, Bethesda, Md; F. Edward Hébert School of Medicine, Uniformed Services University of the Health Sciences, Bethesda, Md.
Robert G MichelettiUniversity of Pennsylvania, Philadelphia, Pa.
Caroline M MitchellMassachusetts General Hospital, Boston, Mass.
Maja MockenhauptMedical Center and Medical Faculty-University of Freiburg, Freiburg, Germany.
David A OstrovUniversity of Florida, Gainesville, Fla.
Rebecca PavlosInstitute for Immunology and Infectious Diseases, Murdoch University, Murdoch, Western Australia, Australia.
Munir PirmohamedUniversity of Liverpool, Liverpool, United Kingdom.
Elena PopeUniversity of Toronto, Toronto, Ontario, Canada; Hospital for Sick Children, Toronto, Ontario, Canada.
Alec RedwoodInstitute for Immunology and Infectious Diseases, Murdoch University, Murdoch, Western Australia, Australia.
Misha RosenbachUniversity of Pennsylvania, Philadelphia, Pa.
Michael D RosenblumUniversity of California, San Francisco, Calif.
Jean-Claude RoujeauUniversity Paris-Est-Créteil, Créteil, France.
Arturo P SaavedraMassachusetts General Hospital, Boston, Mass.
Hajirah N SaeedMassachusetts Eye and Ear, Harvard Medical School, Boston, Mass.
Jeffery P StruewingNational Human Genome Research Institute, National Institutes of Health, Bethesda, Md.
Hirohiko SuekiShowa University School of Medicine, Tokyo, Japan.
Chonlaphat SukasemRamathibodi Hospital, Mahidol University, Bangkok, Thailand.
Cynthia SungDuke-NUS Medical School, Singapore, Singapore; Health Sciences Authority, Singapore, Singapore.
Jason A TrubianoAustin Health, Heidelberg, Victoria, Australia; University of Melbourne, Melbourne, Victoria, Australia.
Jessica WeintraubUS Food and Drug Administration, Silver Spring, Md.
Lisa M WheatleyNational Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Md.
Kristina B WilliamsVanderbilt University Medical Center, Nashville, Tenn.
Brandon WorleyUniversity of Ottawa, Ottawa, Ontario, Canada.
Wen-Hung ChungChang Gung Memorial Hospital, Taipei, Taiwan.
Neil H ShearVanderbilt University Medical Center, Nashville, Tenn.
Elizabeth J PhillipsVanderbilt University Medical Center, Nashville, Tenn; Institute for Immunology and Infectious Diseases, Murdoch University, Murdoch, Western Australia, Australia. Electronic address: elizabeth.j.phillips@vanderbilt.edu.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
Understanding and preventing HLA-associated drug reactionsP50GM115305 · NIGMS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI PHILLIPS, ELIZABETH · 2015 to 2019
$13.0M
Stevens-Johnson Syndrome/Toxic Epidural Necrolysis 2017: Building Multidisciplinary Networks to Drive Science and TranslationR13AR071267 · NIAMS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI PHILLIPS, ELIZABETH · 2017 to 2017
$43k
Medical Research Council MR/L006758/1NCI NIH HHS P30 CA008748NIAMS NIH HHS R13 AR071267NIGMS NIH HHS P50 GM115305
6 · The paper itself

Abstract

Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) is a life-threatening, immunologically mediated, and usually drug-induced disease with a high burden to individuals, their families, and society with an annual incidence of 1 to 5 per 1,000,000. To effect significant reduction in short- and long-term morbidity and mortality, and advance clinical care and research, coordination of multiple medical, surgical, behavioral, and basic scientific disciplines is required. On March 2, 2017, an investigator-driven meeting was held immediately before the American Academy of Dermatology Annual meeting for the central purpose of assembling, for the first time in the United States, clinicians and scientists from multiple disciplines involved in SJS/TEN clinical care and basic science research. As a product of this meeting, this article summarizes the current state of knowledge and expert opinion related to SJS/TEN covering a broad spectrum of topics including epidemiology and pharmacogenomic networks; clinical management and complications; special populations such as pediatrics, the elderly, and pregnant women; regulatory issues and the electronic health record; new agents that cause SJS/TEN; pharmacogenomics and immunopathogenesis; and the patient perspective. Goals include the maintenance of a durable and productive multidisciplinary network that will significantly further scientific progress and translation into prevention, early diagnosis, and management of SJS/TEN.

Indexed as

AgedChildCongresses as TopicEarly DiagnosisElectronic Health RecordsFemaleHumansInterdisciplinary CommunicationMalePregnancyStevens-Johnson SyndromeTranslational Research, BiomedicalUnited StatesElectronic health recordGranulysinHLANetworksPharmacogenomicsPharmacovigilanceStevens-JohnsonT cellsToxic epidermal necrolysis

Identifiers

PMID29310768
PMCPMC5857362

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.