Evidence map›Paper›PMID 29310739›Full record

ArticleEpidemiology and infection2018

Molecular characterisation of measles virus strains among refugees from Central African Republic in Cameroon in 2014.

P K Ndombo, V N Ndze, F D Mbarga, R Anderson, A Acho, J Ebua Chia, A K Njamnshi, P A Rota, D Waku-Kouomou

Open access · bronzeAbstract read
In one paragraph

Article in Epidemiology and infection, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 10 citations in OpenAlex.

  1. A Scoping Review of the Health of African Immigrant and Refugee Children.International journal of environmental research and public health · 2021
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 3 countries.

P K NdomboMother and Child Center, Chantal Biya Foundation,Yaoundé,Cameroon.
V N NdzeMother and Child Center, Chantal Biya Foundation,Yaoundé,Cameroon.
F D MbargaFaculty of Medicine and Biomedical Sciences,University of Yaoundé 1,Yaoundé,Cameroon.
R AndersonDivision of Viral Diseases,National Center for Immunization and Respiratory Diseases, United States Centers for Disease Control and Prevention,Atlanta, Georgia 30333,USA.
A AchoCentral Hospital Yaoundé,Cameroon.
J Ebua ChiaMinistry of Public Health, Yaounde,Cameroon.
A K NjamnshiFaculty of Medicine and Biomedical Sciences,University of Yaoundé 1,Yaoundé,Cameroon.
P A RotaDivision of Viral Diseases,National Center for Immunization and Respiratory Diseases, United States Centers for Disease Control and Prevention,Atlanta, Georgia 30333,USA.
D Waku-KouomouDivision of Viral Diseases,National Center for Immunization and Respiratory Diseases, United States Centers for Disease Control and Prevention,Atlanta, Georgia 30333,USA.
Centers for Disease Control and Prevention · USCentre International De Reference Chantal Biya · CMUniversité de Yaoundé I · CMCentral Hospital of Yaoundé · CMInternational Centre for Genetic Engineering and Biotechnology · ZANational Center for Immunization and Respiratory Diseases · US

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

Measles is a highly infectious human viral disease caused by measles virus (MeV). An estimated 114 900 measles deaths occurred worldwide in 2014. There are currently eight clades (A-H) comprised 24 MeV genotypes. We sought to characterise MeVs among Central African Republic (CAR) refugees during the 2014 measles epidemic in Cameroon. Samples were collected from children <15 years with suspected measles infections in two refugee camps in the east region of Cameroon. Viral RNA was extracted directly from urine samples. RNA detection of MeV RNA was performed with real-time reverse transcription polymerase chain reaction (PCR) to amplify a 634 bp nucleotide fragment of the N gene. The sequence of the PCR product was obtained to determine the genotype. MeV RNA was detected in 25 out of 30 samples from suspected cases, and among the 25 positive samples, MeV sequences were obtained from 20. The MeV strains characterised were all genotype B3. The MeV strains from genotype B3 found in this outbreak were more similar to those circulating in Northern Cameroon in 2010-2011 than to MeV strains circulating in the CAR in 2011. Surveillance system should be improved to focus on refugees for early detection of and response to outbreaks.

Indexed as

Disease OutbreaksCameroonCentral African RepublicGenotypeHumansMeaslesMeasles virusNucleocapsid ProteinsNucleoproteinsPhylogenyRefugeesRNA, ViralSequence Analysis, RNAViral ProteinsNucleocapsid Proteinsnucleoprotein, Measles virusNucleoproteinsRNA, ViralViral ProteinsCameroongenotypesmeasles virusrefugees

Identifiers

PMID29310739
PMCPMC9134531
OpenAlexW2782808735

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.