Metacognitive therapy vs. eye movement desensitization and reprocessing for posttraumatic stress disorder: study protocol for a randomized superiority trial.

Hans M Nordahl, Joar Øveraas Halvorsen, Odin Hjemdal, Mimoza Rrusta Ternava, Adrian Wells

Erratum issued Registry-linked trialAbstract readClinical Trial Protocol

In one paragraph

Article in Trials, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT01955590 (A Randomized Controlled Trial of Metacognitive Therapy and Eye Movement Desensitization and Reprocessing for Posttraumatic Stress Disorder), which is not on this map. Cited by 3 papers.

0numbers the graph read from it

0cells of the map it votes in

3citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01955590 nacompletednot on this map

A Randomized Controlled Trial of Metacognitive Therapy and Eye Movement Desensitization and Reprocessing for Posttraumatic Stress Disorder

TypeinterventionalSponsorNorwegian University of Science and TechnologyRan2012 to 2019Enrolled96ConditionsPosttraumatic Stress DisorderArmsMetacognitive therapy, EMDR, Treatment as usual

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

4 · The record

Corrections and comments

Erratum issued
Correction to: Metacognitive therapy vs. eye movement desensitization and reprocessing for posttraumatic stress disorder: study protocol for a randomized superiority trial.2018

5 · Who and what money

Authors and funding

5 authors.

Hans M NordahlSt. Olavs Hospital HF, Nidaros DPS, P.O. Box 3250, 7006, Trondheim, Norway. hans.nordahl@ntnu.no.

Joar Øveraas HalvorsenSt. Olavs Hospital HF, Nidaros DPS, P.O. Box 3250, 7006, Trondheim, Norway.

Odin HjemdalSt. Olavs Hospital HF, Nidaros DPS, P.O. Box 3250, 7006, Trondheim, Norway.

Mimoza Rrusta TernavaSt. Olavs Hospital HF, Nidaros DPS, P.O. Box 3250, 7006, Trondheim, Norway.

Adrian WellsSchool of Psychological Sciences, University of Manchester, Manchester, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe psychological treatment of choice for patients with severe posttraumatic stress disorder (PTSD) is cognitive behavioural exposure therapy or Eye Movement Desensitisation Reprocessing (EMDR). Whilst these are the most effective treatments, approximately 30-45% of the patients show no significant improvements and follow-up data are sparse. Furthermore, a proportion of patients with severe trauma does not benefit or avoid exposure therapy due to the potential to overwhelm them. Therefore, it is necessary to search for effective methods that do not require exposure. Metacognitive therapy (MCT), a recent treatment approach to PTSD that does not require exposure, has potential strong treatment effects but so far a comparison with EMDR has not been made. METHODS/

designThis study is a two-arm, parallel, randomized, superiority trial comparing the effectiveness of MCT with EMDR. One hundred patients with a primary diagnosis of chronic PTSD will be included and will receive 12 sessions of one of the treatments. The primary outcome is severity of PTSD symptoms assessed with the Posttraumatic Diagnostic Scale (PDS) measured post-treatment (3 months). Secondary outcomes include symptom severity (PDS) and measures of anxiety, depression, metacognitive beliefs at 3-month and 12-month follow up. DISCUSSION: This randomized study is the first to compare MCT with EMDR with 12-month follow-up. The study will indicate the comparative effectiveness of MCT against EMDR and the stability of effects when delivered in an outpatient clinical setting.

trial registrationClinicalTrials.gov, NCT01955590 . Registered on 24 September 2013.

Indexed as

Eye Movement Desensitization ReprocessingMetacognitionChronic DiseaseCognitive Behavioral TherapyComparative Effectiveness ResearchEquivalence Trials as TopicHumansNorwayRandomized Controlled Trials as TopicSeverity of Illness IndexStress Disorders, Post-TraumaticTime FactorsTreatment OutcomeEMDRMetacognitive therapyPosttraumatic stress disorderRandomized controlled trial

Identifiers

PMID29310718

DOI10.1186/s13063-017-2404-7

PMCPMC5759867

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

NCT01955590ClinicalTrials.gov

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.