ArticleBMC infectious diseases2018
Different responses of weather factors on hand, foot and mouth disease in three different climate areas of Gansu, China.
Article in BMC infectious diseases, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.
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Who cites it
15 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Ambient temperature, humidity, and urinary system diseases: a population-based study in Western China.Environmental science and pollution research international · 2022Pooled it
- Association of Short-Term Exposure to Meteorological Factors and Risk of Hand, Foot, and Mouth Disease: A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2020Pooled it
- Article
- Influencing factors of hand, foot, and mouth disease based on structural equation modeling in Hubei, China.Scientific reports · 2025Article
- Assessing the modification impact of vaccination on the relationship of the Discomfort Index with hand, foot, and mouth disease in Guizhou: A multicounty study.PLoS neglected tropical diseases · 2024Article
- Using the Acute Flaccid Paralysis Surveillance System to Identify Cases of Acute Flaccid Myelitis, Australia, 2000‒2018.Emerging infectious diseases · 2022Review
- The Short-term Effects of Temperature on Infectious Diarrhea among Children under 5 Years Old in Jiangsu, China: A Time-series Study (2015-2019).Current medical science · 2021Article
- Spatiotemporal characters and influence factors of hand, foot and mouth epidemic in Xinjiang, China.PloS one · 2021Article
- Spatial-temporal heterogeneity and meteorological factors of hand-foot-and-mouth disease in Xinjiang, China from 2008 to 2016.PloS one · 2021Article
- Effect of climate factors on the incidence of hand, foot, and mouth disease in Malaysia: A generalized additive mixed model.Infectious Disease Modelling · 2021Article
- Estimating the Long-Term Epidemiological Trends and Seasonality of Hemorrhagic Fever with Renal Syndrome in China.Infection and drug resistance · 2021Article
- Short-term effects of meteorological factors, air pollution, and sunspot on childhood hand, foot, and mouth disease in Tianjin, China: a new time series regression, 2014-2018.Environmental science and pollution research international · 2020Article
- Article
- Spatial-temporal heterogeneity of hand, foot and mouth disease and impact of meteorological factors in arid/ semi-arid regions: a case study in Ningxia, China.BMC public health · 2019Article
- Health impact of climate change in cities of middle-income countries: the case of China.British medical bulletin · 2019Review
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12 authors.
Funding
Abstract
backgroundTo determine the linear and non-linear interacting relationships between weather factors and hand, foot and mouth disease (HFMD) in children in Gansu, China, and gain further traction as an early warning signal based on weather variability for HFMD transmission.
methodWeekly HFMD cases aged less than 15 and meteorological information from 2010 to 2014 in Jiuquan, Lanzhou and Tianshu, Gansu, China were collected. Generalized linear regression models (GLM) with Poisson link and classification and regression trees (CART) were employed to determine the combined and interactive relationship of weather factors and HFMD in both linear and non-linear ways.
resultsGLM suggested an increase in weekly HFMD of 5.9% [95% confidence interval (CI): 5.4%, 6.5%] in Tianshui, 2.8% [2.5%, 3.1%] in Lanzhou and 1.8% [1.4%, 2.2%] in Jiuquan in association with a 1 °C increase in average temperature, respectively. And 1% increase of relative humidity could increase weekly HFMD of 2.47% [2.23%, 2.71%] in Lanzhou and 1.11% [0.72%, 1.51%] in Tianshui. CART revealed that average temperature and relative humidity were the first two important determinants, and their threshold values for average temperature deceased from 20 °C of Jiuquan to 16 °C in Tianshui; and for relative humidity, threshold values increased from 38% of Jiuquan to 65% of Tianshui.
conclusionAverage temperature was the primary weather factor in three areas, more sensitive in southeast Tianshui, compared with northwest Jiuquan; Relative humidity's effect on HFMD showed a non-linear interacting relationship with average temperature.
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