Evidence map›Paper›PMID 29310592›Full record

ArticleBMC infectious diseases2018

Characterization of non-tuberculous mycobacterium from humans and water in an Agropastoral area in Zambia.

Ngula Monde, Musso Munyeme, Adrian Muwonge, John Bwalya Muma, Sydney Malama

Abstract read
In one paragraph

Article in BMC infectious diseases, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ngula MondeDepartment of Biomedical Sciences, Tropical Diseases Research Center, P.O.Box 71769, Ndola, Zambia. nkabelenga@yahoo.co.uk.
Musso MunyemeDepartment of Disease Control, School of Veterinary Medicine, University of Zambia, P.O. Box 32379, 10101, Lusaka, Zambia.
Adrian MuwongeUniversity of Edinburgh, Roslin Institute, Easter Bush, Midlothian, Scotland, EH259RG, UK.
John Bwalya MumaDepartment of Disease Control, School of Veterinary Medicine, University of Zambia, P.O. Box 32379, 10101, Lusaka, Zambia.
Sydney MalamaHealth Promotions Unit, Institute of Economic and Social Research, University of Zambia, P.O. Box 30900, Lusaka, Zambia.

Funding

NORHED 001/3467/2013
6 · The paper itself

Abstract

backgroundThe non-tuberculous mycobacteria include those mycobacterium species that are not members of the Mycobacterium tuberculosis complex, the causative agent of pulmonary tuberculosis and Mycobacterium leprae. In Zambia, Non-tuberculous Mycobacteria are gaining recognition as pathogens of public health significance. However, there is scanty information on the isolation and speciation of these organisms for better patient management, consequently reducing the burden of these infections. Given the above information, the thrust of this study was to isolate and characterize NTM from humans and water in Namwala district of Zambia.

methodThis was a cross-sectional study were 153 individuals with suspected TB were sampled from four health facilities in Namwala district, sputum samples were also collected. Additionally, 149 water samples were collected from different water drinking sources such as Tap water, Borehole water, rivers, wells and streams. Standard TB culture methods were employed to isolate Non-tuberculous Mycobacteria and later 16S-23S internal transcribed spacer region Sequencing was employed to characterize NTM.

resultsSeven (7, 4.6%) NTM species were identified from humans with M. arupense (3, 42.9%) being the most common organism, while twenty three (23, 15.4%) NTM were identified from water with the common species being Mycobacterium gordonae (5, 21.7%). Mycobacterium avium and Mycobacterium fortuitum were both identified from human and water samples.

conclusionThis study has shown the isolation of NTM species from humans and water. The isolation of NTM from drinking water sources could signify a public health risk to humans.

Indexed as

Water MicrobiologyCross-Sectional StudiesHumansMycobacterium aviumMycobacterium fortuitumMycobacterium Infections, NontuberculousNontuberculous MycobacteriaPublic HealthSputumZambiaMycobacteriaNamwalaNTMWaterZambia

Identifiers

PMID29310592
PMCPMC5759224

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.