ArticleThe Journal of international medical research2018
Focal segmental glomerulosclerosis in children complicated by posterior reversible encephalopathy syndrome.
Article in The Journal of international medical research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 11 citations in OpenAlex.
- Corticosteroids in posterior reversible encephalopathy syndrome: Friend or foe? A systematic review.World journal of clinical cases · 2025Article
- The Role of Urinary NGAL in the Management of Primary Vesicoureteral Reflux in Children.International journal of molecular sciences · 2023Review
- The Overlap of Kidney Failure in Extrapulmonary Sarcoidosis in Children-Case Report and Review of Literature.International journal of molecular sciences · 2023Review
- Palm-Plant Pain, Sign of a Severe Systemic Disease? Case Report and Review of Literature.Genes · 2023Review
- Thrombosis in Chronic Kidney Disease in Children.Diagnostics (Basel, Switzerland) · 2022Article
- Posterior reversible encephalopathy syndrome associated with focal segmental glomerulosclerosis in a child.BMJ case reports · 2021Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
An uncommon side effect of cyclosporine A (CsA) use is posterior reversible encephalopathy syndrome (PRES). PRES usually develops because of disturbed capacity of posterior cerebral blood flow to autoregulate an acute rise in blood pressure. We present the case of a 10-year-old girl who was previously diagnosed in our department with focal segmental glomerulosclerosis. She was treated with CsA and developed seizures, progressive loss of consciousness, and visual disturbance on the 7th day of treatment. Brain magnetic resonance imaging showed degeneration of white matter with diffuse demyelination in the parietal and posterior occipital lobes, consistent with the diagnosis of PRES. Cases of PRES reported in children are usually secondary to immunosuppressive therapy in oncological and haematological diseases. Our case is the fifth reported case of focal segmental glomerulosclerosis in children treated with CsA and complicated by PRES. Rapid recognition of PRES and stopping neurotoxic therapy early are essential for a good prognosis.
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Registered trials
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