Evidence map›Paper›PMID 29310020›Full record

ArticleLeukemia research2018

Genotypic and clinical heterogeneity within NCCN favorable-risk acute myeloid leukemia.

Stephen A Strickland, Aaron C Shaver, Michael Byrne, Robert D Daber, P Brent Ferrell, David R Head, Sanjay R Mohan, Claudio A Mosse, Tamara K Moyo, Thomas P Stricker and 3 more

Open access · greenAbstract read
In one paragraph

Article in Leukemia research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Differences in prognostic value ofmedRxiv : the preprint server for health sciences · 2025
    Article
  4. What Influences the Decision to Proceed to Transplant for Patients With AML in First Remission?Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2023
    Review
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Stephen A StricklandDivision of Hematology/Oncology, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN, United States; Vanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, United States.
Aaron C ShaverDepartment of Pathology, Microbiology, and Immunology, Vanderbilt University School of Medicine, Nashville, TN, United States.
Michael ByrneDivision of Hematology/Oncology, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN, United States; Vanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, United States.
Robert D DaberBioReference Laboratories, Elmwood Park, NJ, United States.
P Brent FerrellDivision of Hematology/Oncology, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN, United States; Vanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, United States.
David R HeadDepartment of Pathology, Microbiology, and Immunology, Vanderbilt University School of Medicine, Nashville, TN, United States.
Sanjay R MohanDivision of Hematology/Oncology, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN, United States; Vanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, United States.
Claudio A MosseVanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, United States; Department of Pathology, Microbiology, and Immunology, Vanderbilt University School of Medicine, Nashville, TN, United States; Department of Pathology and Laboratory Medicine, VA Tennessee Valley Healthcare System, Nashville, TN, United States.
Tamara K MoyoDivision of Hematology/Oncology, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN, United States; Vanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, United States.
Thomas P StrickerVanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, United States; Department of Pathology, Microbiology, and Immunology, Vanderbilt University School of Medicine, Nashville, TN, United States.
Cindy Vnencak-JonesDepartment of Pathology, Microbiology, and Immunology, Vanderbilt University School of Medicine, Nashville, TN, United States.
Michael R SavonaDivision of Hematology/Oncology, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN, United States; Vanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, United States.
Adam C SeegmillerDepartment of Pathology, Microbiology, and Immunology, Vanderbilt University School of Medicine, Nashville, TN, United States. Electronic address: adam.seegmiller@vanderbilt.edu.
Vanderbilt University · USVA Tennessee Valley Healthcare System · US

Funding

Vanderbilt Institute for Clinical and Translational Research (VICTR) -Identifying correlates of functional immunity in SARS-CoV-2 convalescent plasmaUL1TR002243 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Paul A. Harris, Wesley H Self · 2017 to 2026
$130.7M
The Vanderbilt Institute for Clinical and Translational Research (VICTR)UL1TR000445 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BERNARD, GORDON RAPHAEL · 2012 to 2016
$41.4M
Vanderbilt Clinical Oncology Research Career Development ProgramK12CA090625 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Debra L. Friedman, Paula Jill Hurley · 2001 to 2026
$16.9M
NCATS NIH HHS UL1 TR000445NCATS NIH HHS UL1 TR002243NCI NIH HHS K12 CA090625
6 · The paper itself

Abstract

The National Comprehensive Cancer Network (NCCN) defines the following types of acute myeloid leukemia (AML) as favorable-risk: acute promyelocytic leukemia with t(15;17) (APL); AML with core-binding factor (CBF) rearrangements, including t(8;21) and inv(16) or t(16;16) without mutations in KIT (CBF-KIT

Indexed as

GenotypeAdultAgedAge FactorsCCAAT-Enhancer-Binding ProteinsCore Binding FactorsFemaleGene OrderHumansKaplan-Meier EstimateKaryotypingLeukemia, Myeloid, AcuteMaleMiddle AgedMutationNuclear ProteinsCCAAT-Enhancer-Binding ProteinsCEBPA protein, humanCore Binding FactorsKIT protein, humanNPM1 protein, humanNuclear ProteinsNucleophosminProto-Oncogene Proteins c-kitAcute myeloid leukemiaCore binding factorFavorable riskMolecular diagnostics

Identifiers

PMID29310020
PMCPMC5856485
OpenAlexW2781611671

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.