Evidence map›Paper›PMID 29309958›Full record

ArticlePsychiatry research2018

No differences in manic-like behaviors between voluntary ethanol and water drinking in Lateral Hypothalamic Kindled (LHK) alcohol preferring rats.

Noha Abdel Gawad, Khalid Mohamed, Doo-Sup Choi, Osama A Abulseoud

Open access · greenAbstract read
In one paragraph

Article in Psychiatry research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 100% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Noha Abdel GawadDepartment of Psychiatry and Psychology, Mayo Clinic, Rochester, MN, United States; Department of Psychiatry, University of Texas Health Science Center at Houston and McGovern Medical School, Houston, TX, United States.
Khalid MohamedDepartment of Psychiatry and Psychology, Mayo Clinic, Rochester, MN, United States.
Doo-Sup ChoiDepartment of Psychiatry and Psychology, Mayo Clinic, Rochester, MN, United States; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN, United States.
Osama A AbulseoudDepartment of Psychiatry and Psychology, Mayo Clinic, Rochester, MN, United States; Neuroimaging Research Branch, IRP, National Institute on Drug Abuse, Baltimore, MD, United States. Electronic address: osama.abulseoud@nih.gov.
Mayo Clinic · USNational Institute on Drug Abuse · USWinnMed · US

Funding

Mayo Clinic Center for Translational Science ActivitiesKL2RR024151 · NCRR · MAYO CLINIC ROCHESTER · PI RIZZA, ROBERT A. · 2006 to 2011
$15.3M
Rodents with Genetic Differences in Alcohol PreferenceU24AA015512 · NIAAA · INDIANA UNIVERSITY INDIANAPOLIS · PI BELL, RICHARD LOWELL · 2015 to 2019
$2.7M
Rat Animal Models & Drug and Gene Testing Core (RAM-DGTC)U24AA013522 · NIAAA · INDIANA UNIVERSITY INDIANAPOLIS · PI BELL, RICHARD LOWELL · 2015 to 2021
$2.4M
NCRR NIH HHS KL2 RR024151NIAAA NIH HHS U24 AA013522NIAAA NIH HHS U24 AA015512
6 · The paper itself

Abstract

This study investigates phenotypic differences of manic-like behaviors during voluntary ethanol (vs. water) intake in alcohol preferring (P) rats, using the lateral hypothalamus kindled (LHK) rat mania model. Alcohol preferring (P) rats exhibited classic manic-like behaviors during kindling and the post-kindling intervals in all coded behaviors (p < 0.0001), lending further validity to the lateral hypothalamus kindled rat as a useful model to study mania. However, there was no significant phenotypic difference between alcohol and water drinking alcohol preferring (P) rats.

Indexed as

AggressionAlcohol DrinkingAnimalsBipolar DisorderDrinkingEthanolHypothalamic Area, LateralKindling, NeurologicMalePsychomotor AgitationRatsSpecies SpecificityEthanol

Identifiers

PMID29309958
PMCPMC7770981
OpenAlexW2781992166

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.