Evidence map›Paper›PMID 29309034›Full record

ArticleeLife2018

Inverted formin 2 regulates intracellular trafficking, placentation, and pregnancy outcome.

Katherine Young Bezold Lamm, Maddison L Johnson, Julie Baker Phillips, Michael B Muntifering, Jeanne M James, Helen N Jones, Raymond W Redline, Antonis Rokas, Louis J Muglia

Open access · goldAbstract read
In one paragraph

Article in eLife, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. The multiple links between actin and mitochondria.Nature reviews. Molecular cell biology · 2023
    Review
  6. Article
  7. Article
  8. Review
  9. The formin INF2 in disease: progress from 10 years of research.Cellular and molecular life sciences : CMLS · 2020
    Review
  10. FSGS-Causing INF2 Mutation Impairs Cleaved INF2 N-Fragment Functions in Podocytes.Journal of the American Society of Nephrology : JASN · 2020
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Katherine Young Bezold LammCenter for the Prevention of Preterm Birth, Perinatal Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, United States.ORCID 0000-0001-9803-5743
Maddison L JohnsonDepartment of Biological Sciences, Vanderbilt University, Nashville, United States.
Julie Baker PhillipsDepartment of Biological Sciences, Vanderbilt University, Nashville, United States.
Michael B MuntiferingDivision of Developmental Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, United States.ORCID 0000-0002-0460-4050
Jeanne M JamesThe Heart Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, United States.
Helen N JonesMolecular and Developmental Biology Graduate Program, University of Cincinnati College of Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, United States.
Raymond W RedlineDepartment of Pathology, University Hospitals Cleveland Medical Center, Cleveland, United States.
Antonis RokasDepartment of Biological Sciences, Vanderbilt University, Nashville, United States.ORCID 0000-0002-7248-6551
Louis J MugliaCenter for the Prevention of Preterm Birth, Perinatal Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, United States.
Cincinnati Children's Hospital Medical Center · USVanderbilt University · USUniversity Hospitals of Cleveland · US

Funding

Multi-Photon Confocal MicroscopeS10RR029406 · NCRR · CINCINNATI CHILDRENS HOSP MED CTR · PI ZHENG, YI · 2011 to 2011
$827k
NCRR NIH HHS S10 RR029406
6 · The paper itself

Abstract

Healthy pregnancy depends on proper placentation-including proliferation, differentiation, and invasion of trophoblast cells-which, if impaired, causes placental ischemia resulting in intrauterine growth restriction and preeclampsia. Mechanisms regulating trophoblast invasion, however, are unknown. We report that reduction of

Indexed as

PlacentationAnimalsCell DifferentiationCell MovementFemaleForminsMiceMice, KnockoutMicrofilament ProteinsPregnancyPregnancy OutcomeTrophoblastsForminsINF2 protein, mouseMicrofilament Proteinscell biologydevelopmental biologyextravillous trophoblast invasiongestational hypertensionhumanINF2intrauterine growth restrictionmouseplacentaplacental insufficiencystem cells

Identifiers

PMID29309034
PMCPMC5758111
OpenAlexW2784073980

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.