Evidence map›Paper›PMID 29308654›Full record

ArticleAIDS research and human retroviruses2018

Short Communication: Anatomic Site of Sampling and the Rectal Mucosal Microbiota in HIV Negative Men Who Have Sex with Men Engaging in Condomless Receptive Anal Intercourse.

Nicole A Pescatore, Rebecca Pollak, Colleen S Kraft, Jennifer G Mulle, Colleen F Kelley

Abstract read
In one paragraph

Article in AIDS research and human retroviruses, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Trial
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. HIV, Sexual Orientation, and Gut Microbiome Interactions.Digestive diseases and sciences · 2020
    Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Nicole A Pescatore1 Division of Infectious Diseases, Emory University School of Medicine , Atlanta, Georgia .
Rebecca Pollak3 Department of Human Genetics, Emory University School of Medicine , Atlanta, Georgia .
Colleen S Kraft2 Department of Epidemiology, Rollins School of Public Health, Emory University , Atlanta, Georgia .
Jennifer G Mulle2 Department of Epidemiology, Rollins School of Public Health, Emory University , Atlanta, Georgia .
Colleen F Kelley1 Division of Infectious Diseases, Emory University School of Medicine , Atlanta, Georgia .

Funding

Virology and Molecular Biomarkers CoreP30AI050409 · NIAID · EMORY UNIVERSITY · PI Hannah LF Cooper · 2002 to 2026
$74.0M
Defining the rectal mucosa in MSM at risk of HIV infectionK23AI108335 · NIAID · EMORY UNIVERSITY · PI KELLEY, COLLEEN F · 2013 to 2017
$855k
NIAID NIH HHS K23 AI108335NIAID NIH HHS P30 AI050409
6 · The paper itself

Abstract

Rectal transmission accounts for the majority of HIV transmissions among men who have sex with men (MSM). We previously demonstrated a distinct rectal mucosal immune environment in MSM engaging in condomless receptive anal intercourse (CRAI) compared with men who do not engage in anal intercourse, including enrichment of the microbiota for the Prevotellaceae family as compared with Bacteroidaceae. Here, we expand upon these previous findings to determine differences by anatomic site of collection (anal vs. rectal mucosa) and examine associations of the predominant taxa with other genera. We analyzed 16SrRNA gene sequences of the V1-V2 region generated on an Illumina MiSeq

Indexed as

HIV SeronegativityHomosexuality, MaleHumansMaleMicrobiotaMucous MembraneRectumRisk FactorsRNA, Ribosomal, 16SSequence Analysis, RNAUnsafe SexRNA, Ribosomal, 16SBacteroidesHIV transmissionmicrobiomeMSMPrevotellarectal mucosa

Identifiers

PMID29308654
PMCPMC5863096

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.