Evidence map›Paper›PMID 29308528›Full record

ArticleApplied microbiology and biotechnology2018

Biosynthesis of flavone C-glucosides in engineered Escherichia coli.

Anil Shrestha, Ramesh Prasad Pandey, Dipesh Dhakal, Prakash Parajuli, Jae Kyung Sohng

Abstract read
PubMed Publisher
In one paragraph

Article in Applied microbiology and biotechnology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 51 citations in OpenAlex.

  1. Metabolic engineering ofaBIOTECH · 2026
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  5. Synthesis ofACS omega · 2024
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  6. Review
  7. CRISPR/Cpf1-FOKI-induced gene editing inSynthetic and systems biotechnology · 2024
    Article
  8. Biosynthesis of Apigenin Glucosides in EngineeredJournal of microbiology and biotechnology · 2024
    Article
  9. Biosynthesis and Anticancer Activity of Genistein Glycoside Derivatives.Anti-cancer agents in medicinal chemistry · 2024
    Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. De novo biosynthesis ofBioresources and bioprocessing · 2021
    Article
  17. Review
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Anil Shrestha *Department of Life Science and Biochemical Engineering, Sun Moon University, 70 Sunmoon-ro 221, Tangjeong-myeon, Asan-si, Chungnam, 31460, Republic of Korea.
Ramesh Prasad Pandey *Department of Life Science and Biochemical Engineering, Sun Moon University, 70 Sunmoon-ro 221, Tangjeong-myeon, Asan-si, Chungnam, 31460, Republic of Korea.
Dipesh DhakalDepartment of Life Science and Biochemical Engineering, Sun Moon University, 70 Sunmoon-ro 221, Tangjeong-myeon, Asan-si, Chungnam, 31460, Republic of Korea.
Prakash ParajuliDepartment of Life Science and Biochemical Engineering, Sun Moon University, 70 Sunmoon-ro 221, Tangjeong-myeon, Asan-si, Chungnam, 31460, Republic of Korea.
Jae Kyung SohngDepartment of Life Science and Biochemical Engineering, Sun Moon University, 70 Sunmoon-ro 221, Tangjeong-myeon, Asan-si, Chungnam, 31460, Republic of Korea. sohng@sunmoon.ac.kr.ORCID http://orcid.org/0000-0003-1583-5046
Sun Moon University · KR

Funding

Next-Generation BioGreen 21 Program PJ01111901
6 · The paper itself

Abstract

Two plant-originated C-glucosyltransferases (CGTs) UGT708D1 from Glycine max and GtUF6CGT1 from Gentiana triflora were accessed for glucosylation of selected flavones chrysin and luteolin. Uridine diphosphate (UDP)-glucose pool was enhanced in Escherichia coli cell cytosol by introducing heterologous UDP-glucose biosynthetic genes, i.e., glucokinase (glk), phosphoglucomutase (pgm2), and glucose 1-phosphate uridylyltransferase (galU), along with glucose facilitator diffusion protein from (glf) from different organisms, in a multi-monocistronic vector with individual T

Indexed as

Metabolic EngineeringBatch Cell Culture TechniquesBiosynthetic PathwaysChromatography, High Pressure LiquidEscherichia coliFermentationFlavonesFlavonoidsGentianaGlucokinaseGlucosidesGlucosyltransferasesGlycine maxLuteolinPhosphoglucomutaseSpectrometry, Mass, Electrospray IonizationchrysinflavoneFlavonesFlavonoidsGlucokinaseGlucosidesglucosyltransferase CGlucosyltransferasesLuteolinPhosphoglucomutaseUridine Diphosphate GlucoseC-glucosylationC-glycosyltransferaseChrysinFlavoneLuteolin

Identifiers

PMID29308528
OpenAlexW2782048892

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.