ArticleBiological psychiatry. Cognitive neuroscience and neuroimaging2017
Brain Volume Correlates with Duration of Abstinence from Substance Abuse in a Region-Specific and Substance-Specific Manner.
Article in Biological psychiatry. Cognitive neuroscience and neuroimaging, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed.
- Brain Structure and Substance Use: Disentangling Risk, Exposure, and Drug-Specific Effects.medRxiv : the preprint server for health sciences · 2026Article
- Article
- Adverse childhood experiences, brain function, and psychiatric diagnoses in a large adult clinical cohort.Frontiers in psychiatry · 2024Article
- Hard stop: reestablishing the significance of abstinence in the treatment of late stage ultra-processed food addiction.Frontiers in psychiatry · 2024Article
- Sex Difference in Cigarette-Smoking Status and Its Association with Brain Volumes Using Large-Scale Community-Representative Data.Brain sciences · 2023Article
- The Effects of Alcohol and Cannabis Co-Use on Neurocognitive Function, Brain Structure, and Brain Function.Current behavioral neuroscience reports · 2021Article
- Addiction as a brain disease revised: why it still matters, and the need for consilience.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2021Review
- Disruption of Cigarette Smoking Addiction After Dorsal Striatum Damage.Frontiers in behavioral neuroscience · 2021Article
- Neurocognitive impairment and gray matter volume reduction in HIV-infected patients.Journal of neurovirology · 2020Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Background: Human neuroimaging studies indicate that the loss of brain volume associated with substance abuse may be recovered during abstinence. Subcortical and prefrontal cortical regions involved in reward and decision-making are among the regions most consistently implicated in damage and recovery from substance abuse, but the relative capacities of these different brain regions to recover volume during abstinence remains unclear, and it is unknown whether recovery capacities depend on the substance that was abused. Methods: Voxel-based morphometry in a prison inmate sample ( Results: In FRUs of alcohol, abstinence duration positively correlated with volume in subcortical regions (particularly the putamen and amygdala) but not prefrontal regions; lower prefrontal but not subcortical volume was observed in FRUs compared to FLUs. In FRUs of cocaine, abstinence duration positively correlated with volume in both subcortical regions (particularly the nucleus accumbens) and prefrontal regions; lower volume was not observed in either subcortical or prefrontal regions in FRUs. In FRUs of cannabis, abstinence duration positively correlated with subcortical but not prefrontal volume; lower prefrontal but not subcortical volume was observed in FRUs. Conclusions: Subcortical structures displayed indicators of volume recovery across FRUs of all three substances, whereas prefrontal regions displayed indicators of volume recovery only in FRUs of cocaine.
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