Evidence map›Paper›PMID 29308311›Full record

ArticleOncoimmunology

Increased infiltration of M2-macrophages, T-cells and PD-L1 expression in high grade leiomyosarcomas supports immunotherapeutic strategies.

Marie Kostine, Inge H Briaire-de Bruijn, Arjen H G Cleven, Carly Vervat, Willem E Corver, Marco W Schilham, Els Van Beelen, Hester van Boven, Rick L Haas, Antoine Italiano and 2 more

Open access · goldAbstract read
In one paragraph

Article in Oncoimmunology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 2 pooled it
2.1field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 2 syntheses or guidelines pooled it, 44 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
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  5. Review
  6. Review
  7. Review
  8. Role of Immunotherapy in Sarcomas.International journal of molecular sciences · 2024
    Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. The Landscape of Immunotherapy for Retroperitoneal Sarcoma.Current oncology (Toronto, Ont.) · 2023
    Review
  15. Article
  16. Review
  17. Review
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Marie KostineDepartment of Pathology, Leiden University Medical Center, Leiden, The Netherlands.
Inge H Briaire-de BruijnDepartment of Pathology, Leiden University Medical Center, Leiden, The Netherlands.
Arjen H G ClevenDepartment of Pathology, Leiden University Medical Center, Leiden, The Netherlands.
Carly VervatDepartment of Pediatrics, Leiden University Medical Center, Leiden, The Netherlands.
Willem E CorverDepartment of Pathology, Leiden University Medical Center, Leiden, The Netherlands.
Marco W SchilhamDepartment of Pediatrics, Leiden University Medical Center, Leiden, The Netherlands.
Els Van BeelenDepartment of Immunohematology and Blood Transfusion, Leiden University Medical Center, Albinusdreef 2, ZA Leiden, The Netherlands.
Hester van BovenDepartment of Pathology, Netherlands Cancer Institute - Antoni van Leeuwenhoek, Amsterdam, The Netherlands.
Rick L HaasDepartment of Radiotherapy, Netherlands Cancer Institute - Antoni van Leeuwenhoek, Amsterdam, The Netherlands.
Antoine ItalianoDepartment of Medical Oncology, Institut Bergonié, Bordeaux, France.
Anne-Marie Cleton-JansenDepartment of Pathology, Leiden University Medical Center, Leiden, The Netherlands.
Judith V M G BovéeDepartment of Pathology, Leiden University Medical Center, Leiden, The Netherlands.
Leiden University Medical Center · NLInstitut Bergonié · FRThe Netherlands Cancer Institute · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

HLAleiomyosarcomaPD-L1, immunotherapytumor-associated macrophagestumor-infiltrating lymphocytes

Identifiers

PMID29308311
PMCPMC5749622
OpenAlexW2762910263

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.