Evidence map›Paper›PMID 29308155›Full record

ArticleChemical science2015

Stereocontrolled protein surface recognition using chiral oligoamide proteomimetic foldamers.

Valeria Azzarito, Jennifer A Miles, Julie Fisher, Thomas A Edwards, Stuart L Warriner, Andrew J Wilson

Open access · diamondAbstract read
In one paragraph

Article in Chemical science, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 61 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Selective Affimers Recognise the BCL-2 Family Proteins BCL-xChembiochem : a European journal of chemical biology · 2021
    Article
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  6. Article
  7. Article
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  12. Differential Effects of βAngewandte Chemie (International ed. in English) · 2018
    Article
  13. Article
  14. Article
  15. Article
  16. Probing Protein Surfaces: QSAR Analysis with Helix Mimetics.Chembiochem : a European journal of chemical biology · 2016
    Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Valeria AzzaritoSchool of Chemistry , University of Leeds , Woodhouse Lane , Leeds , LS2 9JT , UK . Email: A.J.Wilson@leeds.ac.uk.
Jennifer A MilesSchool of Chemistry , University of Leeds , Woodhouse Lane , Leeds , LS2 9JT , UK . Email: A.J.Wilson@leeds.ac.uk.
Julie FisherSchool of Chemistry , University of Leeds , Woodhouse Lane , Leeds , LS2 9JT , UK . Email: A.J.Wilson@leeds.ac.uk.
Thomas A EdwardsAstbury Centre for Structural and Molecular Biology , University of Leeds , Woodhouse Lane , Leeds , LS2 9JT , UK.
Stuart L WarrinerSchool of Chemistry , University of Leeds , Woodhouse Lane , Leeds , LS2 9JT , UK . Email: A.J.Wilson@leeds.ac.uk.
Andrew J WilsonSchool of Chemistry , University of Leeds , Woodhouse Lane , Leeds , LS2 9JT , UK . Email: A.J.Wilson@leeds.ac.uk.
University of Leeds · GBInstitute of Structural and Molecular Biology · GB

Funding

European Research Council 240324Wellcome Trust
6 · The paper itself

Abstract

The development of foldamers capable of selective molecular recognition of solvent exposed protein surfaces represents an outstanding challenge in supramolecular chemical biology. Here we introduce an oligoamide foldamer with well-defined conformation that bears all the hallmarks of an information rich oligomer. Specifically, the foldamer recognizes its target protein

Identifiers

PMID29308155
PMCPMC5646261
OpenAlexW2157977328

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.