Evidence map›Paper›PMID 29307993›Full record

ArticleWorld journal of gastroenterology2017

Morin enhances hepatic Nrf2 expression in a liver fibrosis rat model.

Liang Sang, Xue-Mei Wang, Dong-Yang Xu, Li-Xuan Sang, Yang Han, Long-Yang Jiang

Open access · bronzeAbstract read
In one paragraph

Article in World journal of gastroenterology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 53 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Dopamine receptor D1-mediated suppression of liver fibrosisWorld journal of gastroenterology · 2025
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  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Benefits ofBiomedicines · 2023
    Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Liang SangDepartment of Ultrasound, The First Hospital of China Medical University, Shenyang 110001, Liaoning Province, China.
Xue-Mei WangDepartment of Ultrasound, The First Hospital of China Medical University, Shenyang 110001, Liaoning Province, China. wangxuemei@cmu1h.com.
Dong-Yang XuDepartment of Ultrasound, The First Hospital of China Medical University, Shenyang 110001, Liaoning Province, China.
Li-Xuan SangDepartment of Geriatrics, The First Hospital of China Medical University, Shenyang 110001, Liaoning Province, China.
Yang HanDepartment of Pathology, China Medical University, Shenyang 110001, Liaoning Province, China.
Long-Yang JiangPharmacy College, China Medical University, Shenyang 110001, Liaoning Province, China.
China Medical University · CNFirst Hospital of China Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo investigate whether morin can reduce hepatic fibrosis by activating the NF-E2-related factor 2 (Nrf2) signaling pathway.

methodsTwenty male Sprague-Dawley rats were randomly divided into four groups: control group, morin group, carbon tetrachloride (CCl

resultsMorin-treated rats in the morin + CCl

conclusionMorin could play a protective role by inducing the expression of Nrf2 and its downstream antioxidant factors (HO-1 and NQO1) and reducing the expression of α-SMA, collagen I, and collagen III in CCl

Indexed as

AnimalsAntioxidantsCarbon TetrachlorideDisease Models, AnimalFlavonesFlavonoidsHumansLiverLiver CirrhosisLiver Function TestsMaleNF-E2-Related Factor 2Oxidative StressProtective AgentsRatsRats, Sprague-DawleyAntioxidantsCarbon TetrachlorideFlavonesFlavonoidsmorinNfe2l2 protein, ratNF-E2-Related Factor 2Protective AgentsLiver fibrosisMorinNrf2Rat

Identifiers

PMID29307993
PMCPMC5743504
OpenAlexW2776342909

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.