Evidence map›Paper›PMID 29307990›Full record

ArticleWorld journal of gastroenterology2017

Polymorphisms in oxidative pathway related genes and susceptibility to inflammatory bowel disease.

Nezha Senhaji, Sellama Nadifi, Younes Zaid, Aurora Serrano, Daniel Arturo Leon Rodriguez, Nadia Serbati, Mehdi Karkouri, Wafaa Badre, Javier Martín

Open access · hybridAbstract read
In one paragraph

Article in World journal of gastroenterology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Nezha SenhajiLaboratory of Genetic and Molecular Pathology, Faculty of Medicine and Pharmacy of Casablanca, Hassan II University, Casablanca 20100, Morocco. nezha.senhaji05@etude.univcasa.ma.
Sellama NadifiLaboratory of Genetic and Molecular Pathology, Faculty of Medicine and Pharmacy of Casablanca, Hassan II University, Casablanca 20100, Morocco.
Younes ZaidMohammed VI University of Health Sciences, Casablanca 20000, Morocco.
Aurora SerranoInstituto de Parasitología y Biomedicina López-Neyra, Consejo Superior de Investigaciones Científicas, P.T.S. Granada 18016, Spain.
Daniel Arturo Leon RodriguezInstituto de Parasitología y Biomedicina López-Neyra, Consejo Superior de Investigaciones Científicas, P.T.S. Granada 18016, Spain.
Nadia SerbatiLaboratory of Genetic and Molecular Pathology, Faculty of Medicine and Pharmacy of Casablanca, Hassan II University, Casablanca 20100, Morocco.
Mehdi KarkouriDepartment of Pathology, CHU Ibn Rochd, Casablanca 20000, Morocco.
Wafaa BadreDepartment of Gastroenterology, CHU Ibn Rochd, Casablanca 20000, Morocco.
Javier MartínInstituto de Parasitología y Biomedicina López-Neyra, Consejo Superior de Investigaciones Científicas, P.T.S. Granada 18016, Spain.
Instituto de Parasitología y Biomedicina "López - Neyra" · ESUniversity of Hassan II Casablanca · MACentre Hospitalier Universitaire Ibn Rochd · MAUniversité Mohammed VI des Sciences de la Santé · MA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo investigate whether common variants in the oxidative pathway genes influence inflammatory bowel disease (IBD) risk among Moroccan patients.

methodsThe distribution of (TAAA)n_rs12720460 and (CCTTT)n _rs3833912

resultsThe allele and genotype frequencies of

conclusionOur results suggest that the

Indexed as

Genetic Predisposition to DiseaseAdolescentAdultAllelesFemaleHaplotypesHumansHypoxia-Inducible Factor 1, alpha SubunitInflammatory Bowel DiseasesMaleMicrosatellite RepeatsMoroccoNF-kappa B p50 SubunitNitric Oxide Synthase Type IIOxidative StressPolymorphism, Single NucleotideHIF1A protein, humanHypoxia-Inducible Factor 1, alpha SubunitNF-kappa B p50 SubunitNFKB1 protein, humanNitric Oxide Synthase Type IINOS2 protein, humanHIF1AInflammatory bowel diseaseMoroccan patientsNFKB1NOS2A

Identifiers

PMID29307990
PMCPMC5743501
OpenAlexW2952546703

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.