ArticleIndian journal of anaesthesia2017
Perfusion index as a predictor of hypotension following propofol induction - A prospective observational study.
Article in Indian journal of anaesthesia, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04217226 (Evaluation of Perfusion Index-derived Parameters as Predictors of Hypotension After Induction of General Anaesthesia), which is not on this map. Cited by 19 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Evaluation of Perfusion Index-derived Parameters as Predictors of Hypotension After Induction of General Anaesthesia: a Prospective Cohort Study.
Who cites it
19 citing papers in PubMed, 38 citations in OpenAlex.
- Comparison of the Efficacy of Ciprofol and Propofol for Rapid Sequence Induction and Intubation in Elective Non-Cardiac Surgery: A Prospective, Randomized, Non-Inferiority Trial.Drug design, development and therapy · 2026Trial
- Observer's Assessment of Alertness/Sedation-based titration reduces propofol consumption and incidence of hypotension during general anesthesia induction: A randomized controlled trial.Science progress · 2021Trial
- Hemodynamic impact of increasing time between fentanyl and propofol administration during anesthesia induction: a randomised, clinical trial.Brazilian journal of anesthesiology (Elsevier)Trial
- Role of the inferior vena cava collapsibility index in predicting propofol-induced hypotension in patients undergoing colonoscopy.BMC anesthesiology · 2025Article
- The Use of the Perfusion Index to Predict Post-Induction Hypotension in Patients Undergoing General Anesthesia: A Systematic Review and Meta-Analysis.Diagnostics (Basel, Switzerland) · 2024Review
- Carotid blood flow changes following a simulated end-inspiratory occlusion maneuver measured by ultrasound can predict hypotension after the induction of general anesthesia: an observational study.BMC anesthesiology · 2024Observational
- Predictive Ability of Perfusion Index for Determining the Success of Adductor Canal Nerve Block for Postoperative Analgesia in Patients Undergoing Unilateral Total Knee Arthroplasty.Life (Basel, Switzerland) · 2023Article
- Prediction of hypotension during the alveolar recruitment maneuver in spine surgery: a prospective observational study.European journal of medical research · 2023Observational
- To ascertain the plasma concentration of propofol to achieve bispectral index-guided sedation using a target-controlled infusion in patients undergoing elective surgeries under neuraxial anaesthesia.Indian journal of anaesthesia · 2022Article
- Article
- The Perfusion Index of the Ear as a Predictor of Hypotension Following the Induction of Anesthesia in Patients with Hypertension: A Prospective Observational Study.Journal of clinical medicine · 2022Article
- Article
- Evaluation of perfusion index as an objective tool to assess analgesia during laparoscopic surgeries under general anaesthesia.Indian journal of anaesthesia · 2022Article
- Perfusion index-derived parameters as predictors of hypotension after induction of general anaesthesia: a prospective cohort study.Anaesthesiology intensive therapy · 2022Observational
- Correlation between the Perfusion Index and Intraoperative Hypothermia: A Prospective Observational Pilot Study.Medicina (Kaunas, Lithuania) · 2021Observational
- Caval aorta index as a predictor of hypotension after spinal anesthesia in patients with diabetes mellitus - A cross-sectional comparative study.Journal of anaesthesiology, clinical pharmacologyArticle
- A Prospective Observational Study of Plethysmograph Variability Index and Perfusion Index in Predicting Hypotension with Propofol Induction in Noncardiac Surgeries.Anesthesia, essays and researchesArticle
- Perfusion index to predict post spinal hypotension in lower segment caesarean section.Journal of anaesthesiology, clinical pharmacologyArticle
- Ultrasound Measurement of Inferior Vena Cava Collapsibility as a Tool to Predict Propofol-Induced Hypotension.Anesthesia, essays and researchesArticle
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
aimsHypotension during propofol induction is a common problem. Perfusion index (PI), an indicator of systemic vascular resistance, is said to be predictive of hypotension following subarachnoid block. We hypothesised that PI can predict hypotension following propofol induction and a cut-off value beyond which hypotension is more common can be determined.
methodsFifty adults belonging to the American Society of Anesthesiologists' physical status I/II undergoing elective surgery under general anaesthesia were enrolled for this prospective, observational study. PI, heart rate, blood pressure (BP) and oxygen saturation were recorded every minute from baseline to 10 min following induction of anaesthesia with a titrated dose of propofol, and after endotracheal intubation. Hypotension was defined as fall in systolic BP (SBP) by >30% of baseline or mean arterial pressure (MAP) to <60 mm Hg. Severe hypotension (MAP of <55 mm Hg) was treated.
resultsWithin first 5-min after induction, the incidence of hypotension with SBP and MAP criteria was 30% and 42%, respectively, and that of severe hypotension, 22%. Baseline PI <1.05 predicted incidence of hypotension at 5 min with sensitivity 93%, specificity 71%, positive predictive value (PPV) 68% and negative predictive value (NPV) 98%. The area under the ROC curve (AUC) was 0.816, 95% confidence interval (0.699-0.933),
conclusionPerfusion index could predict hypotension following propofol induction, especially before endotracheal intubation, and had a very high negative predictive value.
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