Evidence map›Paper›PMID 29307864›Full record

ArticleJournal of the American Heart Association2018

Long-Term Exposure of Fine Particulate Matter Causes Hypertension by Impaired Renal D

Xi Lu, Zhengmeng Ye, Shuo Zheng, Hongmei Ren, Jing Zeng, Xinquan Wang, Pedro A Jose, Ken Chen, Chunyu Zeng

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.2field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
  2. Article
  3. G protein-coupled receptor kinases in hypertension: physiology, pathogenesis, and therapeutic targets.Hypertension research : official journal of the Japanese Society of Hypertension · 2024
    Review
  4. Dopamine Receptor DThe Yale journal of biology and medicine · 2023
    Review
  5. Review
  6. Article
  7. Article
  8. Review
  9. Review
  10. Particulate Matter and Albuminuria, Glomerular Filtration Rate, and Incident CKD.Clinical journal of the American Society of Nephrology : CJASN · 2020
    Article
  11. Article
  12. Kidney dopamine DAmerican journal of physiology. Renal physiology · 2019
    Article
  13. The Role of Myokines and Adipokines in Hypertension and Hypertension-related Complications.Hypertension research : official journal of the Japanese Society of Hypertension · 2019
    Observational
  14. Article
  15. The emerging role of sorting nexins in cardiovascular diseases.Clinical science (London, England : 1979) · 2019
    Review
  16. In Vitro and In Vivo Experimental Studies of PMInternational journal of environmental research and public health · 2018
    Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Xi LuDepartment of Cardiology, Daping Hospital, The Third Military Medical University, Chongqing, China.
Zhengmeng YeDepartment of Cardiology, Daping Hospital, The Third Military Medical University, Chongqing, China.
Shuo ZhengDepartment of Cardiology, Daping Hospital, The Third Military Medical University, Chongqing, China.
Hongmei RenDepartment of Cardiology, Daping Hospital, The Third Military Medical University, Chongqing, China.
Jing ZengDepartment of Cardiology, Daping Hospital, The Third Military Medical University, Chongqing, China.
Xinquan WangDepartment of Cardiology, Daping Hospital, The Third Military Medical University, Chongqing, China.
Pedro A JoseDivision of Renal Disease and Hypertension, The George Washington University School of Medicine and Health Sciences, Washington, DC.
Ken ChenDepartment of Cardiology, Daping Hospital, The Third Military Medical University, Chongqing, China chunyuzeng01@163.com chenken0205@yahoo.com.
Chunyu ZengDepartment of Cardiology, Daping Hospital, The Third Military Medical University, Chongqing, China chunyuzeng01@163.com chenken0205@yahoo.com.
Army Medical University · CNDaping Hospital · CNGeorge Washington University · US

Funding

Spatiotemporal transregulation of D1-like angiotensin receptors in genetically...P01HL074940 · NHLBI · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI JOSE, PEDRO A. · 2004 to 2020
$31.8M
Renal Dopamine Receptor & RegulationR37HL023081 · NHLBI · UNIVERSITY OF MARYLAND BALTIMORE · PI JOSE, PEDRO A. · 2007 to 2016
$4.3M
RENAL DOPAMINE RECEPTOR REGULATION AND FUNCTIONR01HL023081 · NHLBI · GEORGETOWN UNIVERSITY · PI JOSE, PEDRO A. · 1985 to 2006
$2.4M
NHLBI NIH HHS P01 HL074940NHLBI NIH HHS R01 HL023081NHLBI NIH HHS R37 HL023081
6 · The paper itself

Abstract

backgroundEpidemiological evidence supports an important association between air pollution exposure and hypertension. However, the mechanisms are not clear. METHODS AND

resultsOur present study found that long-term exposure to fine particulate matter (PM

conclusionsOur present study indicated that long-term exposure of PM

Indexed as

AnimalsBlood PressureCell LineG-Protein-Coupled Receptor Kinase 4HypertensionKidney Tubules, ProximalMaleNatriuresisParticle SizeParticulate MatterPhosphorylationRats, Inbred WKYRats, Sprague-DawleyReactive Oxygen SpeciesReceptors, Dopamine D1Renal EliminationG-Protein-Coupled Receptor Kinase 4Grk4 protein, ratParticulate MatterReactive Oxygen SpeciesReceptors, Dopamine D1Sodiumdopamine receptorGRK4hypertensionkidneyPM 2.5sodium excretion

Identifiers

PMID29307864
PMCPMC5778966
OpenAlexW2782329248

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.