Evidence map›Paper›PMID 29307722›Full record

Trial reportOsteoarthritis and cartilage2018

Physical therapy vs internet-based exercise training for patients with knee osteoarthritis: results of a randomized controlled trial.

K D Allen, L Arbeeva, L F Callahan, Y M Golightly, A P Goode, B C Heiderscheit, K M Huffman, H H Severson, T A Schwartz

2 registry-linked trialsAbstract readComparative StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Osteoarthritis and cartilage, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 71 papers, 26 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
71citing papers in PubMed, 26 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02312713 nacompletednot on this map

Physical Therapy Versus Internet-Based Exercise Training for Patients With Knee Osteoarthritis

TypeinterventionalSponsorUniversity of North Carolina, Chapel HillRan2014 to 2017Enrolled350ConditionsKnee OsteoarthritisArmsInternet Based Exercise Training, Physical Therapy
NCT06416332 naunknown statusnot on this mapstarted 2022, after this paper: background citation

Development and Implementation of a Tele -Rehabilitation System for Patients With Knee Osteoarthritis (Aged 40-70 Years, Kellgren Grade 1-3 and Lawrence )

TypeinterventionalSponsorUniversity of West AtticaRan2022 to 2024Enrolled34ConditionsKnee Osteoarthritis, Knee Osteoarthritis \(OA\), TelerehabilitationArmsgroup A: in face to face live therapeutic exercise, group B: telerehabilitation program
3 · Its place in the literature

Who cites it

71 citing papers in PubMed, 26 syntheses or guidelines pooled it.

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  10. Exercise for osteoarthritis of the knee.The Cochrane database of systematic reviews · 2024
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11 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

K D AllenThurston Arthritis Research Center, University of North Carolina at Chapel Hill, 3300 Thurston Bldg., CB# 7280, Chapel Hill, NC 27599, USA; Department of Medicine, University of North Carolina at Chapel Hill, 125 MacNider Hall, CB# 7005 Chapel Hill, NC 27599, USA; Center for Health Services Research in Primary Care, Durham VA Medical Center, Durham, NC, USA. Electronic address: kdallen@email.unc.edu.
L ArbeevaThurston Arthritis Research Center, University of North Carolina at Chapel Hill, 3300 Thurston Bldg., CB# 7280, Chapel Hill, NC 27599, USA; Department of Medicine, University of North Carolina at Chapel Hill, 125 MacNider Hall, CB# 7005 Chapel Hill, NC 27599, USA. Electronic address: liubov_arbeeva@med.unc.edu.
L F CallahanThurston Arthritis Research Center, University of North Carolina at Chapel Hill, 3300 Thurston Bldg., CB# 7280, Chapel Hill, NC 27599, USA; Department of Medicine, University of North Carolina at Chapel Hill, 125 MacNider Hall, CB# 7005 Chapel Hill, NC 27599, USA. Electronic address: leigh_callahan@med.unc.edu.
Y M GolightlyThurston Arthritis Research Center, University of North Carolina at Chapel Hill, 3300 Thurston Bldg., CB# 7280, Chapel Hill, NC 27599, USA; Injury Prevention Research Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. Electronic address: golight@email.unc.edu.
A P GoodeDuke Clinical Research Institute, Durham, NC, USA; Department of Orthopedic Surgery, Division of Physical Therapy, Duke University Medical Center, USA. Electronic address: adam.goode@duke.edu.
B C HeiderscheitDepartment of Orthopedics and Rehabilitation, University of Wisconsin-Madison, Madison, WI, USA. Electronic address: heiderscheit@ortho.wisc.edu.
K M HuffmanDepartment of Medicine, Division of Rheumatology, Duke University Medical Center, Durham, NC, USA; Physical Medicine and Rehabilitation Service, Durham VA Medical Center, Durham, NC, USA. Electronic address: kim.huffman@duke.edu.
H H SeversonOregon Research Institute, Eugene, OR, USA. Electronic address: herb@ori.org.
T A SchwartzThurston Arthritis Research Center, University of North Carolina at Chapel Hill, 3300 Thurston Bldg., CB# 7280, Chapel Hill, NC 27599, USA; Department of Biostatistics, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA; School of Nursing, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. Electronic address: Todd_Schwartz@unc.edu.

Funding

Patient-Centered Outcomes Research Institute CER-1306-02043
6 · The paper itself

Abstract

objectiveTo compare the effectiveness of physical therapy (PT, evidence-based approach) and internet-based exercise training (IBET), each vs a wait list (WL) control, among individuals with knee osteoarthritis (OA).

designRandomized controlled trial of 350 participants with symptomatic knee OA, allocated to standard PT, IBET and WL control in a 2:2:1 ratio, respectively. The PT group received up to eight individual visits within 4 months. The IBET program provided tailored exercises, video demonstrations, and guidance on progression. The primary outcome was the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC, range 0 [no problems]-96 [extreme problems]), assessed at baseline, 4 months (primary time point) and 12 months. General linear mixed effects modeling compared changes in WOMAC among study groups, with superiority hypotheses testing differences between each intervention group and WL and non-inferiority hypotheses comparing IBET with PT.

resultsAt 4-months, improvements in WOMAC score did not differ significantly for either the IBET or PT group compared with WL (IBET: -2.70, 95% Confidence Interval (CI) = -6.24, 0.85, P = 0.14; PT: -3.36, 95% (CI) = -6.84, 0.12, P = 0.06). Similarly, at 12-months mean differences compared to WL were not statistically significant for either group (IBET: -2.63, 95% CI = -6.37, 1.11, P = 0.17; PT: -1.59, 95% CI = -5.26, 2.08, P = 0.39). IBET was non-inferior to PT at both time points.

conclusionsImprovements in WOMAC score following IBET and PT did not differ significantly from the WL group. Additional research is needed to examine strategies for maximizing benefits of exercise-based interventions for patients with knee OA.

trial registrationNCT02312713.

Indexed as

ExercisePhysical Therapy ModalitiesAgedFemaleHumansInternetMaleMiddle AgedOsteoarthritis, KneeTreatment OutcomeInternetKneeOsteoarthritisPhysical activityPhysical therapy

Identifiers

PMID29307722
PMCPMC6021028

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.