Evidence map›Paper›PMID 29307065›Full record

ArticleEnvironmental science and pollution research international2018

Metals in bones of the middle-aged inhabitants of Sardinia island (Italy) to assess nutrition and environmental exposure.

Beatrice Bocca, Giovanni Forte, Valentina Giuffra, Rita Maria Serra, Yolande Asara, Cristiano Farace, Marco Milanese, Eugenia Tognotti, Andrea Montella, Pasquale Bandiera and 1 more

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Article in Environmental science and pollution research international, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Beatrice BoccaItalian National Institute for Health, Viale Regina Elena 299, 00161, Rome, Italy.
Giovanni ForteItalian National Institute for Health, Viale Regina Elena 299, 00161, Rome, Italy. giovanni.forte@iss.it.ORCID http://orcid.org/0000-0001-5779-9333
Valentina GiuffraDivision of Paleopathology, Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy.
Rita Maria SerraCentre for Anthropological, Paleopathological and Historical Studies of the Sardinian and Mediterranean Populations, Department of Biomedical Sciences, University of Sassari, Sassari, Italy.
Yolande AsaraDepartment of Biomedical Sciences-Histology, University of Sassari, Sassari, Italy.
Cristiano FaraceDepartment of Biomedical Sciences-Histology, University of Sassari, Sassari, Italy.
Marco MilaneseDepartment of History, Human Sciences and Education, University of Sassari, Sassari, Italy.
Eugenia TognottiDepartment of Biomedical Sciences-Histology, University of Sassari, Sassari, Italy.
Andrea MontellaDepartment of Biomedical Sciences-Histology, University of Sassari, Sassari, Italy.
Pasquale BandieraCentre for Anthropological, Paleopathological and Historical Studies of the Sardinian and Mediterranean Populations, Department of Biomedical Sciences, University of Sassari, Sassari, Italy.
Roberto MadedduDepartment of Biomedical Sciences-Histology, University of Sassari, Sassari, Italy.
University of Sassari · ITNational Institute of Health · AMUniversity of Pisa · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Metals in bones of 72 subjects lived between the twelfth and eighteenth century AC and collected in four Sardinian (Italian insular region) burial sites (Alghero, Bisarcio, Geridu, and Sassari) were determined and used as biomarkers to evaluate diet and potential social-environmental differences. Concentrations of Ba, Ca, Cd, Cu, Hg, Pb, Sr, and Zn were quantified in different types of compact bone (femur, fibula, humerus, radius, tibia, ulna) by sector field inductively coupled plasma mass spectrometry previous acidic digestion and differences among the various burial sites, centuries, types of bone, gender, and age were explored by univariate and multivariate analyses. Results indicated differences between sites in terms of diet: Bisarcio (inland village) had increased ratios of Ba/Ca and Zn/Ca due to higher incidence of vegetables, cereals, and animal foods in the diet; Geridu (coastal village) showed increased Sr/Ca ratio indicating foods of plant and marine origin that were predominant; Alghero (coastal site) and Sassari (inland site) displayed prevalently a mixed diet reflecting a higher economy and food imports. In addition, these latter sites showed increased levels of Hg/Ca (fish, drugs, cosmetics) and Pb/Ca (coins, utensils, pipeline for water). In conclusion, the elemental Ba/Ca, Sr/Ca, and Zn/Ca ratios were indicative of provenance and diet, while Hg/Ca and Pb/Ca ratios were associated to various forms of environmental exposure.

Indexed as

AnimalsBariumBone and BonesDietEnvironmental ExposureEnvironmental MonitoringFishesHumansIslandsItalyMercuryMetalsMiddle AgedNutritional StatusBariumMercuryMetalsBonesDietEnvironmentMetalsMiddle ageSardinia

Identifiers

PMID29307065
OpenAlexW2781989013

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.