Evidence map›Paper›PMID 29306970›Full record

ArticleEuropean journal of trauma and emergency surgery : official publication of the European Trauma Society2018

Preoperative decolonization to reduce infections in urgent lower extremity repairs.

Daniel S Urias, Merin Varghese, Thomas Simunich, Shawna Morrissey, Russell Dumire

Abstract read
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In one paragraph

Article in European journal of trauma and emergency surgery : official publication of the European Trauma Society, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

  1. Pooled it
  2. Universal decolonization for methicillin-resistantPublic health in practice (Oxford, England) · 2026
    Article
  3. Article
  4. Living with dogs and cats: Is it a risk factor for community acquired methicillin-resistantRevista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2025
    Article
  5. Intranasal Testing and Treatment forJournal of the Pediatric Orthopaedic Society of North America · 2025
    Article
  6. Review
  7. Article
  8. Article
  9. Preoperative Intranasal Decolonization with Topical Povidone-Iodine Antiseptic and the Incidence of Surgical Site Infection: A Review.Medical science monitor : international medical journal of experimental and clinical research · 2020
    Review
  10. Review
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Daniel S UriasConemaugh Memorial Medical Center, 1086 Franklin Street GS G54, Johnstown, PA, 15905, USA. durias@conemaugh.org.
Merin VargheseConemaugh Memorial Medical Center, 1086 Franklin Street GS G54, Johnstown, PA, 15905, USA.
Thomas SimunichConemaugh Memorial Medical Center, 1086 Franklin Street GS G54, Johnstown, PA, 15905, USA.
Shawna MorrisseyConemaugh Memorial Medical Center, 1086 Franklin Street GS G54, Johnstown, PA, 15905, USA.
Russell DumireConemaugh Memorial Medical Center, 1086 Franklin Street GS G54, Johnstown, PA, 15905, USA.
Conemaugh Health System · USConemaugh Memorial Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeMedical implants and surgical site infections (SSIs) can be a burden on both patients and healthcare systems with a significant rise in morbidity, mortality and costs. Preoperatively, our practice of a chlorohexidine gluconate (CHG) washcloth bath or solution shower was supplemented with nasal painting using povidone-iodine skin and nasal antiseptic (PI-SNA). We sought to measure the effectiveness in reducing SSIs in patients undergoing repair of lower extremity fractures.

methodsA retrospective review of trauma patients undergoing orthopedic operations conducted at Conemaugh Memorial Medical Center from 10/1/2012 through 9/30/2016. The intervention period was 10/1/2014 to 9/30/2016 which included the addition of nasal painting with PI-SNA preoperatively. All patients were followed for 1 year prior to January 2013 and 30 or 90 days thereafter for the development of a SSI.

resultsThe pre-intervention group consisted of 930 cases with a 1.1% infection rate (10 SSIs). The intervention group consisted of 962 cases with a 0.2% infection rate (2 SSIs). This observed difference was statistically significant (P = 0.020).

conclusionsThis retrospective review of a methicillin-resistant Staphylococcus aureus decolonization protocol using CHG bath/shower and PI-SNA nasal painting revealed a significant decrease in the infection rate of patients undergoing lower extremity fracture repairs. We recommend its use without contraindications, but recognize that additional investigations are necessary.

Indexed as

Administration, IntranasalAdultAgedAnti-Infective Agents, LocalBathsCarrier StateChlorhexidineFemaleHumansLeg InjuriesMaleMethicillin-Resistant Staphylococcus aureusMiddle AgedPovidone-IodineRetrospective StudiesStaphylococcal InfectionsAnti-Infective Agents, LocalChlorhexidinePovidone-IodineDecolonizationFracturesMRSAPovidone-iodineSurgical site infectionTrauma

Identifiers

PMID29306970
OpenAlexW2782299297

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.