Evidence map›Paper›PMID 29306901›Full record

ArticleJournal of the American Heart Association2018

Cardiometabolic Health Among Adult Offspring of Hypertensive Pregnancies: The Cardiovascular Risk in Young Finns Study.

Robyn J Tapp, Alun D Hughes, Mika Kähönen, Tien Yin Wong, Nicholas Witt, Terho Lehtimäki, Nina Hutri-Kähönen, Pinki Sahota, Markus Juonala, Olli T Raitakari

Open access · goldAbstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of the American Heart Association, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 4 pooled it
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 4 syntheses or guidelines pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Review
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 9 institutions in 4 countries.

Robyn J TappMelbourne School of Population and Global Health University of Melbourne, Australia robyn.tapp@unimelb.edu.au.
Alun D HughesInstitute of Cardiovascular Science, University College London, London, United Kingdom.
Mika KähönenDepartment of Clinical Physiology, Tampere University Hospital and the University of Tampere, Finland.
Tien Yin WongSingapore National Eye Center, Singapore & Ophthalmology and Visual Sciences Academic Clinical Program, Duke-NUS Medical School, National University of Singapore, Singapore.
Nicholas WittNational Heart and Lung Institute, Imperial College London, London, United Kingdom.
Terho LehtimäkiDepartment of Clinical Chemistry, Fimlab Laboratories and School of Medicine, University of Tampere, Finland.
Nina Hutri-KähönenDepartment of Pediatrics, University of Tampere and Tampere University Hospital, Tampere, Finland.
Pinki SahotaSchool of Clinical and Applied Sciences, Leeds Beckett University, Leeds, United Kingdom.
Markus JuonalaResearch Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Finland.
Olli T RaitakariResearch Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Finland.
University of Turku · FIFimlab (Finland) · FIImperial College London · GBLeeds Beckett University · GBSingapore National Eye Center · SGTampere University · FITampere University Hospital · FIUniversity College London · GBUniversity of Melbourne · AU

Funding

British Heart Foundation CS/15/6/31468British Heart Foundation PG/12/29/29497
6 · The paper itself

Abstract

backgroundCardiometabolic health among adult offspring of hypertensive disorders of pregnancy (HDP) is relatively unknown. We hypothesized that offspring of HDP would have abnormalities in the retinal microvasculature and cardiac structure by midadulthood. METHODS AND

resultsThe Cardiovascular Risk in Young Finns Study included randomly selected children from 5 Finnish university cities. The mean age of participants was 40 years (range 34-49 years) at the time of retinal photography and cardiac assessment. Offspring born ≥37 weeks of gestation and appropriate for gestational age (n=1006) were included. Offspring of HDP had higher systolic blood pressure (β=4.68,

conclusionsAbnormalities of the retinal microvasculature and cardiac structure are seen in offspring of HDP in midadulthood. These findings may need to be considered in future primary prevention strategies of cardiovascular disease among offspring of HDP.

Indexed as

Blood PressurePrenatal Exposure Delayed EffectsAdultAge FactorsEchocardiographyFemaleHeart DiseasesHumansHypertension, Pregnancy-InducedMaleMaternal HealthMicrovesselsMiddle AgedPhotographyPregnancyPrognosiscardiachealth outcomesmicrovascular dysfunction

Identifiers

PMID29306901
PMCPMC5778953
OpenAlexW2782516664

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.