SynthesisBMC cancer2018
Relationship between the extent of resection and the survival of patients with low-grade gliomas: a systematic review and meta-analysis.
Synthesis in BMC cancer, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 2 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
50 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Extent of resection in diffuse low-grade gliomas and the role of tumor molecular signature-a systematic review of the literature.Neurosurgical review · 2021Pooled it
- PSMA-Targeting Positron Emission Agents for Imaging Solid Tumors Other Than Non-Prostate Carcinoma: A Systematic Review.International journal of molecular sciences · 2019Pooled it
- MRI-based clinical radiomics nomogram for the prognostic prediction of adult diffuse low-grade gliomas.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026Article
- Subtotal tumor resection as a predictor of post-resection hydrocephalus in pediatric patients with posterior fossa tumors.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2025Article
- MYCN amplification defines an aggressive phenotype in IDH-mutant gliomas.The journal of pathology. Clinical research · 2025Article
- Extension of TNMR in biomedicine · 2025Article
- Microscope integrated MHz optical coherence tomography system for neurosurgery: development and clinical in-vivo imaging.Biomedical optics express · 2024Article
- Facilitating complete resection of intrinsic motor cortex glioma with titration of high-frequency cortico-subcortical mapping train count informed by navigated transcranial magnetic stimulation: illustrative case.Journal of neurosurgery. Case lessons · 2024Article
- Experience in awake glioma surgery in a South American center. Correlation between intraoperative evaluation, extent of resection and functional outcomes.World neurosurgery: X · 2024Article
- Mechanical characteristics of glioblastoma and peritumoral tumor-free human brain tissue.Acta neurochirurgica · 2024Article
- Applying the en-bloc technique in corpus callosum glioblastoma surgery contributes to maximal resection and better prognosis: a retrospective study.BMC surgery · 2024Article
- Surgical Management and Advances in the Treatment of Glioma.Seminars in neurology · 2023Review
- The dynamic functional connectivity fingerprint of high-grade gliomas.Scientific reports · 2023Article
- Identification and validation of RNA methylation-related alternative splicing gene signature for low-grade glioma to predict survival and immune landscapes.Journal of cancer research and clinical oncology · 2023Article
- Intraoperative use of low-field magnetic resonance imaging for brain tumors: A systematic review.Surgical neurology international · 2023Review
- Benign Glioma.Advances in experimental medicine and biology · 2023Article
- Flavin fluorescence lifetime and autofluorescence optical redox ratio for improved visualization and classification of brain tumors.Frontiers in oncology · 2023Article
- Early costs and complications of first-line low-grade glioma treatment using a large national database: Limitations and future perspectives.Frontiers in surgery · 2023Article
- TMIGD2 as a potential therapeutic target in glioma patients.Frontiers in immunology · 2023Article
- Magnetic Resonance-Guided Laser Interstitial Thermal Therapy for Management of Low-Grade Gliomas and Radiation Necrosis: A Single-Institution Case Series.Brain sciences · 2022Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSurgical resection is necessary to conduct a pathological biopsy and to achieve a reduction of intracranial pressure in low-grade gliomas patients. This study aimed to determine whether a greater extent of resection would increase the overall 5-year and 10-year survival of patients with low-grade gliomas.
methodsThe studies addressing relationship between the extent of resection and the prognosis of low-grade gliomas updated until March 2017 were systematically searched in two databases (Pubmed and EMBASE). The relationships among categorical variables were analyzed using an odds ratio (OR) and a95% confidence interval (CI). Significance was established using CIs at a level of 95% or P < 0.05. Funnel plot was used to detect the publication bias.
resultsTwenty articles (a total of 2128 patients) were identified. The meta-analysis showed that the 5-year (Odds ratio (OR), 3.90;95% Confidence Interval (CI), 2.79~5.45; P < 0.01; Z = 7.95) and 10-year OS (OR, 7.91; 95%CI, 5.12~12.22; P < 0.01; Z = 9.33) associated with gross total resection (GTR) were higher than those associated with subtotal resection (STR). Similarly, as compared with biopsy(BX), the 5-year and 10-year OS were higher after either GTR (5-year: OR, 5.43; 95%CI, 3.57~8.26; P < 0.01; Z = Z = 7.9; 10-year: OR, 10.17; 95%CI, 4.02~25.71; P < 0.00001; Z = 4.9) or STR (5-year: OR, 2.59; 95%CI, 1.81~ - 3.71; P < 0.00001; Z = 5.19; 10-year: OR, 2.21; 95%CI, 1.164.25; P = 0.02; Z = 2.39).
conclusionsOur research found that a greater extent of resection could significantly increase the OS of patients with low-grade gliomas.
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