Evidence map›Paper›PMID 29306015›Full record

ReviewCancer letters2018

Long noncoding RNAs: Undeciphered cellular codes encrypting keys of colorectal cancer pathogenesis.

Taewan Kim, Carlo M Croce

Open access · hybridAbstract readReview
In one paragraph

Review in Cancer letters, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 57 citations in OpenAlex.

  1. Article
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  3. LncRNAInternational journal of biological sciences · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Taewan KimThe Ohio State University Comprehensive Cancer Center, Columbus, OH 43210, USA. Electronic address: kim.2203@buckeyemail.osu.edu.
Carlo M CroceDepartment of Cancer Biology and Genetics, College of Medicine, The Ohio State University, Columbus, OH 43210, USA. Electronic address: carlo.croce@osumc.edu.
The Ohio State University · US

Funding

Cancer Gene Discovery to Identify Targetable TargetsR35CA197706 · NCI · OHIO STATE UNIVERSITY · PI CROCE, CARLO M · 2015 to 2021
$6.4M
Identifying non-coding RNAs for early detection and prevention of lung cancerU01CA166905 · NCI · OHIO STATE UNIVERSITY · PI CROCE, CARLO M, PASS, HARVEY IRA · 2013 to 2017
$4.5M
Molecular Mechanisms of Cachexia in Lung CancerR01CA190740 · NCI · OHIO STATE UNIVERSITY · PI CROCE, CARLO M, NANASINKAM, SERGE PATRICK · 2015 to 2019
$2.1M
NCI NIH HHS R01 CA190740NCI NIH HHS R35 CA197706NCI NIH HHS U01 CA166905
6 · The paper itself

Abstract

Long noncoding RNAs are non-protein coding transcripts longer than 200 nucleotides in length. By the advance in genetic and bioinformatic technologies, the new genomic landscape including noncoding transcripts has been revealed. Despite their non-capacity to be translated into proteins, lncRNAs have a versatile functions through various mechanisms interacting with other cellular molecules including DNA, protein, and RNA. Recent research interest and endeavor have identified the functional role of lncRNAs in various diseases including cancer. Colorectal cancer (CRC) is not only one of the most frequent cancer but also one of the cancer types with remarkable achievements in lncRNA research. Of the numerous notable lncRNAs identified and characterized in CRC, we will focus on key lncRNAs with the high potential as CRC-specific biomarkers in this review.

Indexed as

Gene Expression Regulation, NeoplasticBiomarkers, TumorColorectal NeoplasmsGene Expression ProfilingGenome, HumanHumansMutationRNA, Long NoncodingSignal TransductionBiomarkers, TumorRNA, Long NoncodingCancer-associated region long noncoding RNA (CARLo)Colorectal cancer associated transcript (CCAT)Colorectal cancer (CRC)Colorectal Neoplasia Differentially Expressed (CRNDE)Long noncoding RNAs (lncRNA)MYC-regulated long noncoding RNA (MYCLo)

Identifiers

PMID29306015
PMCPMC5825189
OpenAlexW2782238352

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.