Evidence map›Paper›PMID 29305745›Full record

ArticleAmino acids2018

Evaluation of peptides release using a natural rubber latex biomembrane as a carrier.

M C R Miranda, F A Borges, N R Barros, N A Santos Filho, R J Mendonça, R D Herculano, E M Cilli

Abstract read
PubMed Publisher
In one paragraph

Article in Amino acids, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Biomaterials and Contraception: Promises and Pitfalls.Annals of biomedical engineering · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

M C R MirandaInstituto de Química, UNESP, Universidade Estadual Paulista, Rua Prof. Francisco Degni, 55, Araraquara, São Paulo, 14800-060, Brazil.
F A BorgesInstituto de Química, UNESP, Universidade Estadual Paulista, Rua Prof. Francisco Degni, 55, Araraquara, São Paulo, 14800-060, Brazil.
N R BarrosInstituto de Química, UNESP, Universidade Estadual Paulista, Rua Prof. Francisco Degni, 55, Araraquara, São Paulo, 14800-060, Brazil.
N A Santos FilhoInstituto de Química, UNESP, Universidade Estadual Paulista, Rua Prof. Francisco Degni, 55, Araraquara, São Paulo, 14800-060, Brazil.
R J MendonçaCiências Biológicas Department, UFTM, Universidade Federal do Triângulo Mineiro, Uberaba, Minas Gerais, Brazil.
R D HerculanoInstituto de Química, UNESP, Universidade Estadual Paulista, Rua Prof. Francisco Degni, 55, Araraquara, São Paulo, 14800-060, Brazil. rond@fcfar.unesp.br.
E M CilliInstituto de Química, UNESP, Universidade Estadual Paulista, Rua Prof. Francisco Degni, 55, Araraquara, São Paulo, 14800-060, Brazil. cilli@iq.unesp.br.

Funding

SUBTHRESHOLD MUSCLE AFFERENT INPUT TO DORSAL HORNF06TW002012 · FIC · UNIVERSITY OF CALIFORNIA DAVIS · PI KAUFMAN, MARC PETER · 1995 to 1995
–
Conselho Nacional de Desenvolvimento Científico e Tecnológico 301512/2015-9Conselho Nacional de Desenvolvimento Científico e Tecnológico 470261/2012-9Fundação de Amparo à Pesquisa do Estado de São Paulo 2012/15346-7Fundação de Amparo à Pesquisa do Estado de São Paulo 2015/02343-8Fundação de Amparo à Pesquisa do Estado de São Paulo (BR) 2011/17411-8
6 · The paper itself

Abstract

The biomembrane natural (NRL-Natural Rubber Latex), manipulated from the latex obtained from the rubber tree Hevea brasiliensis, has shown great potential for application in biomedicine and biomaterials. Reflecting the biocompatibility and low bounce rate of this material, NRL has been used as a physical barrier to infectious agents and for the controlled release of drugs and extracts. The aim of the present study was to evaluate the incorporation and release of peptides using a latex biomembrane carrier. After incorporation, the release of material from the membrane was observed using spectrophotometry. Analyses using HPLC and mass spectroscopy did not confirm the release of the antimicrobial peptide [W

Indexed as

Drug CarriersMembranes, ArtificialPeptidesDrug Evaluation, PreclinicalHeveaLatexDrug CarriersLatexMembranes, ArtificialPeptidesBiomaterialDrug deliveryNatural rubber latexPeptides

Identifiers

PMID29305745

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.