Evidence map›Paper›PMID 29305536›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2018

POU6f1 Mediates Neuropeptide-Dependent Plasticity in the Adult Brain.

Cynthia K McClard, Mikhail Y Kochukov, Isabella Herman, Zhandong Liu, Aiden Eblimit, Yalda Moayedi, Joshua Ortiz-Guzman, Daniel Colchado, Brandon Pekarek, Sugi Panneerselvam and 2 more

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.4field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Single-cell profiling identifies ACEScience advances · 2023
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Neuropeptide Signaling Networks and Brain Circuit Plasticity.Journal of experimental neuroscience · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 3 countries.

Cynthia K McClardDepartment of Molecular and Human Genetics.
Mikhail Y KochukovDepartment of Molecular and Human Genetics.ORCID 0000-0002-8012-5246
Isabella HermanMedical Scientist Training Program.
Zhandong LiuDepartment of Pediatrics at Texas Children's Hospital.
Aiden EblimitHuman Genome Sequencing Center, Department of Molecular and Human Genetics.ORCID 0000-0002-7743-6385
Yalda MoayediDepartment of Neuroscience, Baylor College of Medicine, Houston, Texas 77030, and.ORCID 0000-0002-0600-1253
Joshua Ortiz-GuzmanProgram in Developmental Biology.
Daniel ColchadoRice University, Houston, Texas 77005.ORCID 0000-0003-0767-0069
Brandon PekarekDepartment of Molecular and Human Genetics.
Sugi PanneerselvamRice University, Houston, Texas 77005.
Graeme MardonDepartment of Molecular and Human Genetics.ORCID 0000-0003-4265-4072
Benjamin R ArenkielDepartment of Molecular and Human Genetics, arenkiel@bcm.edu.ORCID 0000-0001-9047-2420
Baylor College of Medicine · USInstitute of Developmental Physiology · RUUniversity of Houston · USHuman Genome Sciences (United States) · USNational Student Clearinghouse Research Center · USNeurological Research Institute · US

Funding

Tumor BiologyP30CA125123 · NCI · BAYLOR COLLEGE OF MEDICINE · PI DAVID R ROWLEY · 2007 to 2026
$73.9M
Steps towards a paternal gene activation therapy for Angelman syndromeU54HD083092 · NICHD · BAYLOR COLLEGE OF MEDICINE · PI BEAUDET, ARTHUR L., NELSON, DAVID LOREN · 2014 to 2019
$7.8M
R01 Application:Genetically Dissecting Cholinergic Signaling in Body Weight Control.R01DK109934 · NIDDK · BAYLOR COLLEGE OF MEDICINE · PI Benjamin R Arenkiel, Qingchun Tong · 2016 to 2026
$5.4M
MAPPING CONNECTIVITY ONTO POSTNATAL-BORN NEURONSR01NS078294 · NINDS · BAYLOR COLLEGE OF MEDICINE · PI ARENKIEL, BENJAMIN R · 2012 to 2023
$3.6M
Tecan EVO GenePaint robotS10OD016167 · OD · BAYLOR COLLEGE OF MEDICINE · PI LJUNGBERG, CECILIA · 2013 to 2013
$215k
TRANSCRIPTIONAL PROGRAMS GOVERNING ACTIVITY-DEPENDENT MATURATION OF ADULT-BORN NEURONSF31NS092435 · NINDS · BAYLOR COLLEGE OF MEDICINE · PI MCCLARD, CYNTHIA KIM · 2015 to 2016
$87k
NCI NIH HHS P30 CA125123NICHD NIH HHS U54 HD083092NIH HHS S10 OD016167NINDS NIH HHS F31 NS092435NINDS NIH HHS R01 NS078294
6 · The paper itself

Abstract

The mouse olfactory bulb (OB) features continued, activity-dependent integration of adult-born neurons, providing a robust model with which to examine mechanisms of plasticity in the adult brain. We previously reported that local OB interneurons secrete the neuropeptide corticotropin-releasing hormone (CRH) in an activity-dependent manner onto adult-born granule neurons and that local CRH signaling promotes expression of synaptic machinery in the bulb. This effect is mediated via activation of the CRH receptor 1 (

Indexed as

AnimalsBehavior, AnimalBrainCorticotropin-Releasing HormoneCRF Receptor, Type 1FemaleGene Knock-In TechniquesMaleMiceMice, KnockoutNeuronal PlasticityNeuronsNeuropeptidesOctamer Transcription Factor-3Olfactory BulbReceptors, Corticotropin-Releasing HormoneCorticotropin-Releasing HormoneCRF Receptor, Type 1NeuropeptidesOctamer Transcription Factor-3Pou5f1 protein, mouseReceptors, Corticotropin-Releasing Hormoneadult-born neuronsCRHdevelopmentneuropeptidesolfactorysynapse

Identifiers

PMID29305536
PMCPMC5815346
OpenAlexW2781608166

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.