Evidence map›Paper›PMID 29305530›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2018

Role of Purinergic Receptor P2Y1 in Spatiotemporal Ca

Eiji Shigetomi, Yukiho J Hirayama, Kazuhiro Ikenaka, Kenji F Tanaka, Schuichi Koizumi

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
4.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 42 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. P2Y1 receptor in Alzheimer's disease.Neural regeneration research · 2025
    Article
  5. Review
  6. Electrocalcium coupling in brain capillaries: Rapidly traveling electrical signals ignite local calcium signals.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  7. Disease-relevant upregulation of P2YNature communications · 2024
    Article
  8. Article
  9. Review
  10. Review
  11. Review
  12. AβCellular and molecular life sciences : CMLS · 2022
    Article
  13. Article
  14. Cytokine Signalling at the Microglial Penta-Partite Synapse.International journal of molecular sciences · 2021
    Review
  15. Article
  16. Article
  17. Review
  18. Nucleotide P2YPurinergic signalling · 2020
    Article
  19. Update of P2Y receptor pharmacology: IUPHAR Review 27.British journal of pharmacology · 2020
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Eiji ShigetomiDepartment of Neuropharmacology, University of Yamanashi, Yamanashi 409-3898, Japan.ORCID 0000-0002-5267-6155
Yukiho J HirayamaDepartment of Neuropharmacology, University of Yamanashi, Yamanashi 409-3898, Japan.ORCID 0000-0002-3629-6603
Kazuhiro IkenakaDivision of Neurobiology and Bioinformatics, National Institute for Physiological Sciences, Okazaki 444-8787, Japan, and.
Kenji F TanakaDepartment of Neuropsychiatry, School of Medicine, Keio University, Tokyo 160-8582, Japan.ORCID 0000-0003-2511-0057
Schuichi KoizumiDepartment of Neuropharmacology, University of Yamanashi, Yamanashi 409-3898, Japan, skoizumi@yamanashi.ac.jp.ORCID 0000-0001-6184-3106
University of Yamanashi · JPKeio University · JPNational Institute for Physiological Sciences · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fine processes of astrocytes enwrap synapses and are well positioned to sense neuronal information via synaptic transmission. In rodents, astrocyte processes sense synaptic transmission via Gq-protein coupled receptors (GqPCR), including the P2Y1 receptor (P2Y1R), to generate Ca

Indexed as

AnimalsAstrocytesCalcium SignalingFemaleHippocampusMaleMiceMice, TransgenicProbenecidPurinergic P2Y Receptor AntagonistsReceptors, Purinergic P2Y1SynapsesProbenecidPurinergic P2Y Receptor AntagonistsReceptors, Purinergic P2Y1astrocyteastrocyte processATPcalciumGECIP2Y1 receptor

Identifiers

PMID29305530
PMCPMC6705847
OpenAlexW2782519641

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.