Evidence map›Paper›PMID 29305285›Full record

ArticleAmerican journal of infection control2018

National Healthcare Safety Network laboratory-identified Clostridium difficile event reporting: A need for diagnostic stewardship.

Clare Rock, Zoi Pana, Surbhi Leekha, Polly Trexler, Jennifer Andonian, Avinash Gadala, Karen C Carroll, Lisa L Maragakis, CDC Prevention Epicenters Program

Abstract read
In one paragraph

Article in American journal of infection control, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Antimicrobial stewardship & healthcare epidemiology : ASHE · 2025
    Article
  2. Article
  3. Informing estimates of probability ofAntimicrobial stewardship & healthcare epidemiology : ASHE · 2024
    Article
  4. Infection control and hospital epidemiology · 2023
    Article
  5. Association between prevalence of laboratory-identifiedInfection control and hospital epidemiology · 2022
    Article
  6. Clinical Decision Support Systems to Reduce Unnecessary Clostridioides difficile Testing Across Multiple Hospitals.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2022
    Article
  7. Diagnostic Stewardship in the Pediatric Intensive Care Unit.Infectious disease clinics of North America · 2022
    Review
  8. Article
  9. Improving Stewardship ofKansas journal of medicine · 2022
    Article
  10. Article
  11. Clinical impact of aJAC-antimicrobial resistance · 2020
    Article
  12. Article
  13. The Role of Diagnostic Stewardship inCurrent infectious disease reports · 2020
    Article
  14. Article
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Clare RockDepartment of Medicine, Division of Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, MD; Armstrong Institute for Patient Safety and Quality, Johns Hopkins University School of Medicine, Baltimore, MD; Department of Hospital Epidemiology and Infection Control, Johns Hopkins Hospital, Baltimore, MD. Electronic address: clare.rock@jhmi.edu.
Zoi PanaDepartment of Medicine, Division of Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, MD.
Surbhi LeekhaDepartment of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, MD.
Polly TrexlerDepartment of Hospital Epidemiology and Infection Control, Johns Hopkins Hospital, Baltimore, MD.
Jennifer AndonianDepartment of Hospital Epidemiology and Infection Control, Johns Hopkins Hospital, Baltimore, MD.
Avinash GadalaDepartment of Hospital Epidemiology and Infection Control, Johns Hopkins Hospital, Baltimore, MD.
Karen C CarrollDepartment of Pathology, Division of Medical Microbiology, Johns Hopkins University School of Medicine, Baltimore, MD.
Lisa L MaragakisDepartment of Medicine, Division of Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, MD; Armstrong Institute for Patient Safety and Quality, Johns Hopkins University School of Medicine, Baltimore, MD; Department of Hospital Epidemiology and Infection Control, Johns Hopkins Hospital, Baltimore, MD.
CDC Prevention Epicenters Program

Funding

NCEZID CDC HHS U01 CK000554NCEZID CDC HHS U54 CK000447
6 · The paper itself

Abstract

We describe the proportion of health care facility-onset Clostridium difficile infection (HO-CDI) National Healthcare Safety Network laboratory-identified events at our facility that were deemed nontrue HO-CDIs. Reasons included testing in a patient without significant diarrhea or with recent laxative use, or delayed testing. Standardized infection ratios using only true HO-CDI in the numerator were improved compared with publically reported standardized infection ratios. A prioritization matrix identifies which clinical services could benefit most from directed diagnostic stewardship interventions.

Indexed as

Clinical Laboratory Information SystemsDrug UtilizationHealth FacilitiesAnti-Bacterial AgentsClostridioides difficileClostridium InfectionsDisease NotificationHumansPublic Health SurveillanceUnited StatesAnti-Bacterial AgentsFacility reimbursementFacility reputationHealth care-onset infectionInappropriate testingNucleic acid amplification tests

Identifiers

PMID29305285
PMCPMC6734925

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.