Evidence map›Paper›PMID 29304802›Full record

ArticleBMC veterinary research2018

Evaluation of the influence of kyphosis and scoliosis on intervertebral disc extrusion in French bulldogs.

Maria Claudia C M Inglez de Souza, Richard Ryan, Gert Ter Haar, Rowena M A Packer, Holger A Volk, Steven De Decker

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC veterinary research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
4.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Diagnostic Imaging in Intervertebral Disc Disease.Frontiers in veterinary science · 2020
    Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 2 countries.

Maria Claudia C M Inglez de SouzaDepartment of Surgery, University of São Paulo-School of Veterinary Medicine and Animal Science, Av. Prof. Dr. Orlando Marques de Paiva, 87, São Paulo, Cidade Universitária, Brazil.
Richard RyanDepartment of Clinical Science and Services, Royal Veterinary College, University of London, Hawkshead lane, AL9 7TA North Mymms, Hatfield, UK.
Gert Ter HaarDepartment of Clinical Science and Services, Royal Veterinary College, University of London, Hawkshead lane, AL9 7TA North Mymms, Hatfield, UK.
Rowena M A PackerDepartment of Clinical Science and Services, Royal Veterinary College, University of London, Hawkshead lane, AL9 7TA North Mymms, Hatfield, UK.
Holger A VolkDepartment of Clinical Science and Services, Royal Veterinary College, University of London, Hawkshead lane, AL9 7TA North Mymms, Hatfield, UK.
Steven De DeckerDepartment of Clinical Science and Services, Royal Veterinary College, University of London, Hawkshead lane, AL9 7TA North Mymms, Hatfield, UK. sdedecker@rvc.ac.uk.ORCID http://orcid.org/0000-0002-2505-2152
University of London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlthough thoracic vertebral malformations with kyphosis and scoliosis are often considered incidental findings on diagnostic imaging studies of screw-tailed brachycephalic breeds, they have been suggested to interfere with spinal biomechanics and intervertebral disc degeneration. It is however unknown if an abnormal spinal curvature also predisposes dogs to develop clinically relevant intervertebral disc herniations. The aim of this study was to evaluate if the occurrence of thoracic vertebral malformations, kyphosis or scoliosis would be associated with a higher prevalence of cervical or thoracolumbar intervertebral disc extrusion in French bulldogs.

resultsFrench bulldogs that underwent computed tomography for reasons unrelated to spinal disease (n = 101), and French bulldogs with thoracolumbar (n = 47) or cervical intervertebral disc extrusion (n = 30) that underwent magnetic resonance imaging were included. There was a significant association between the presence of kyphosis and the occurrence of intervertebral disc extrusion, particularly in the thoracolumbar region. Dogs with kyphosis were at nearly a two times increased odds of being affected by intervertebral disc extrusion than those without kyphosis [(OR = 1.98 (95% CI: 1.04-3.78)]. There was also an association between the presence of scoliosis and the anatomical distribution of intervertebral disc extrusions, with dogs with scoliosis more likely to have more caudal lumbar intervertebral disc extrusions. Presence of scoliosis was not associated with an increased odds of being affected by intervertebral disc extrusion.

conclusionsAlthough thoracic vertebral malformations with kyphosis only rarely cause spinal cord dysfunction in itself, French bulldogs with kyphosis appear to be at higher risk to develop thoracolumbar intervertebral disc extrusion.

Indexed as

AnimalsDog DiseasesDogsFemaleIntervertebral Disc DegenerationIntervertebral Disc DisplacementKyphosisMagnetic Resonance ImagingMaleScoliosisSpecies SpecificityThoracic VertebraeTomography, X-Ray ComputedBrachycephalicHemivertebraIntervertebral disc diseaseIntervertebral disc herniationVertebral malformation

Identifiers

PMID29304802
PMCPMC5756331
OpenAlexW2781819483

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.