ArticleBMC cancer2018
Attributable causes of colorectal cancer in China.
Article in BMC cancer, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 100 papers, 4 of them syntheses that pooled it.
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Who cites it
100 citing papers in PubMed, 4 syntheses or guidelines pooled it, 158 citations in OpenAlex.
- Population Attributable Fraction of Established Modifiable Risk Factors on Colorectal Cancer in Korea.Cancer research and treatment · 2021Pooled it
- Pooled it
- The association between rs16917496 T/C polymorphism ofBioscience reports · 2018Pooled it
- Dietary Flavonoids and the Risk of Colorectal Cancer: An Updated Meta-Analysis of Epidemiological Studies.Nutrients · 2018Pooled it
- Association between dietary intake and the prevalence of tumourigenic bacteria in the gut microbiota of middle-aged Japanese adults.Scientific reports · 2020Trial
- Development of an Interpretable Triage Tool for Colorectal Polyp Risk Stratification Within a Population-Based Screening Program: Machine Learning Approach.JMIR medical informatics · 2026Article
- Emerging trends in the global burden of colorectal cancer.Nature reviews. Clinical oncology · 2026Review
- Trends and burden of colon and rectum cancer attributable to low physical activity in China: a comprehensive analysis from 1990 to 2021.Cancer causes & control : CCC · 2026Article
- Trends and future burden of major digestive system cancers in Jiangsu Province, China, 2010-2030.Frontiers in oncology · 2026Article
- The mechanism of Akkermansia muciniphila inhibiting the proliferation of colorectal cancer cells via ferroptosis.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026Article
- Association of lifestyle and dietary preferences with precancerous serrated polyps: a hospital-based case-control study in Guangzhou, China.BMC gastroenterology · 2025Article
- Diagnostic Value of Dual Energy Technology of Dual Source CT in Differentiation Grade of Colorectal Cancer.Current medical imaging · 2025Article
- Exploring the gut microbiota associated with peripheral nerve invasion in colorectal cancer patients and constructing predictive models.BMC microbiology · 2025Article
- Colorectal cancer epidemiology (1990-2050): lessons from the Australasian experience.Journal of translational medicine · 2025Article
- Cancer Education Status in China (2013-2022).Journal of cancer education : the official journal of the American Association for Cancer Education · 2025Review
- Cancers attributable to diet in Italy.International journal of cancer · 2025Article
- Deciphering the impact of dietary habits and behavioral patterns on colorectal cancer.International journal of surgery (London, England) · 2025Review
- Comprehensive genomic analysis in sporadic early-onset colorectal adenocarcinoma patients.BMC cancer · 2025Article
- Burden of colon and rectum cancer attributable to processed meat consumption in China, 1990-2021.Frontiers in nutrition · 2025Article
- Overcoming underestimation of the share of colorectal cancer cases attributable to excess weight: a population-based study.Obesity (Silver Spring, Md.) · 2025Article
40 more citing papers are in PubMed but not listed here.
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundColorectal cancer is the 4th common cancer in China. Most colorectal cancers are due to modifiable lifestyle factors, but few studies have provided a systematic evidence-based assessment of the burden of colorectal cancer incidence and mortality attributable to the known risk factors in China.
methodsWe estimated the population attributable faction (PAF) for each selected risk factor in China, based on the prevalence of exposure around 2000 and relative risks from cohort studies and meta-analyses.
resultsAmong 245,000 new cases and 139,000 deaths of colorectal cancer in China in 2012, we found that 115,578 incident cases and 63,102 deaths of colorectal cancer were attributable to smoking, alcohol drinking, overweight and obesity, physical inactivity and dietary factors. Low vegetable intake was the main risk factor for colorectal cancer with a PAF of 17.9%. Physical inactivity was responsible for 8.9% of colorectal cancer incidence and mortality. The remaining factors, including high red and processed meat intake, low fruit intake, alcohol drinking, overweight/obesity and smoking, accounted for 8.6%, 6.4%, 5.4%, 5.3% and 4.9% of colorectal cancer, respectively. Overall, 45.5% of colorectal cancer incidence and mortality were attributable to the joint effects of these seven risk factors.
conclusionsTobacco smoking, alcohol drinking, overweight or obesity, physical inactivity, low vegetable intake, low fruit intake, and high red and processed meat intake were responsible for nearly 46% of colorectal cancer incidence and mortality in China in 2012. Our findings could provide a basis for developing guidelines of colorectal cancer prevention and control in China.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.