Evidence map›Paper›PMID 29304756›Full record

ArticleBMC infectious diseases2018

Medical treatment of an unusual cerebral hydatid disease.

Shu Chen, Ning Li, Feifei Yang, Jiqin Wu, Yuekai Hu, Shenglei Yu, Qi Chen, Xuan Wang, Xinyu Wang, Yuanyuan Liu and 1 more

Open access · goldAbstract readCase Reports
In one paragraph

Article in BMC infectious diseases, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. An Imported Case of Disseminated Echinococcosis in Korea.The Korean journal of parasitology · 2019
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Shu ChenDepartment of infectious diseases, Huashan Hospital, Fudan University, Shanghai, China.
Ning LiDepartment of infectious diseases, Huashan Hospital, Fudan University, Shanghai, China.
Feifei YangDepartment of infectious diseases, Huashan Hospital, Fudan University, Shanghai, China.
Jiqin WuDepartment of infectious diseases, Huashan Hospital, Fudan University, Shanghai, China.
Yuekai HuDepartment of infectious diseases, Huashan Hospital, Fudan University, Shanghai, China.
Shenglei YuDepartment of infectious diseases, Huashan Hospital, Fudan University, Shanghai, China.
Qi ChenDepartment of infectious diseases, Huashan Hospital, Fudan University, Shanghai, China.
Xuan WangDepartment of infectious diseases, Huashan Hospital, Fudan University, Shanghai, China.
Xinyu WangDepartment of infectious diseases, Huashan Hospital, Fudan University, Shanghai, China.
Yuanyuan LiuDepartment of infectious diseases, Huashan Hospital, Fudan University, Shanghai, China.
Jianming ZhengDepartment of infectious diseases, Huashan Hospital, Fudan University, Shanghai, China. zhengjianming@fudan.edu.cn.ORCID 0000-0003-1471-9078
Fudan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHydatid disease is a worldwide zoonosis produced by the larval stage of cestodes of the Echinococcus genus. Hydatid disease primarily involves the liver and lungs. The brain is involved in less than 2% of cases. Surgery has long been the only choice for the treatment, but chemotherapy has been successfully replaced surgery in some special cases. CASE PRESENTATION: We report a rare hydatid disease case which presented with multiple lesions in right frontal lobe, an uncommon site, and in the liver and lungs. A 28-year-old woman presented with 6 months history of recurrent convulsion. Cranial magnetic resonance imaging found multiple lesions in right frontal lobe, so she was hospitalized for surgical treatment and received sodium valproate by oral for controlling epilepsy. Before the operation, other lesions were found in the liver and lungs by computerized tomography scan. There were multiple pulmonary nodules near the pleura and large cyst in the liver. The pathology of liver showed that it may be a hydatid disease. Then, positive serum antibodies for echinococcus antigen further confirmed our diagnosis. Since her central nerve system was involved, she received four pills (800 mg, about 17 mg/kg/day) albendazole treatment for 18 months without operation. Her symptoms abated and a follow-up magnetic resonance imaging showed that the lesion had obviously diminished after treatment. She was recurrence free 2 years after we stopped albendazole treatment.

conclusionsThis case reveals an uncommon pattern of intracranial hydatid disease. Albendazole can be beneficial for some inoperable cerebral hydatid disease patients.

Indexed as

AdultAlbendazoleAnticestodal AgentsBrainEchinococcosisFemaleHumansLiverLungMagnetic Resonance ImagingTomography, X-Ray ComputedAlbendazoleAnticestodal AgentsAlbendazoleBrainHydatid disease

Identifiers

PMID29304756
PMCPMC5756415
OpenAlexW2781854238

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.