Evidence map›Paper›PMID 29304207›Full record

ReviewThe Journal of antimicrobial chemotherapy2018

Changes in the epidemiological landscape of invasive candidiasis.

Frederic Lamoth, Shawn R Lockhart, Elizabeth L Berkow, Thierry Calandra

Open access · bronzeAbstract readReview
In one paragraph

Review in The Journal of antimicrobial chemotherapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 309 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
309citing papers in PubMed, 1 pooled it
25.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

309 citing papers in PubMed, 1 synthesis or guideline pooled it, 528 citations in OpenAlex.

  1. Pooled it
  2. Alkylamidobetaines Induced Changes in Multidrug-Resistant, BiofilmingInternational journal of molecular sciences · 2026
    Article
  3. Article
  4. Article
  5. mBio · 2026
    Article
  6. New Perspectives on Antimicrobial Agents: Fosmanogepix.Antimicrobial agents and chemotherapy · 2026
    Review
  7. Voriconazole Activity AgainstMolecules (Basel, Switzerland) · 2026
    Article
  8. Recent Outbreaks, Resistance Trends, and Control Measures inJournal of fungi (Basel, Switzerland) · 2026
    Review
  9. Article
  10. Overview of Risk Factors and Diagnosis of Invasive Candidiasis.Journal of fungi (Basel, Switzerland) · 2026
    Review
  11. Antifungal Activity ofInternational journal of molecular sciences · 2026
    Article
  12. Article
  13. Review
  14. Article
  15. Review
  16. Article
  17. Clinical characteristics and risk factors of mortality in patients with candidemia: a four-year retrospective study.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Article
  18. Temporal changes in fungal epidemiology in ICU post-operative peritonitis cases.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Article
  19. Article
  20. Article

249 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Frederic LamothInfectious Diseases Service, Department of Medicine, Lausanne University, Lausanne, Switzerland.
Shawn R LockhartMycotic Diseases Branch, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Elizabeth L BerkowMycotic Diseases Branch, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Thierry CalandraInfectious Diseases Service, Department of Medicine, Lausanne University, Lausanne, Switzerland.
Centers for Disease Control and Prevention · USUniversity of Lausanne · CH

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

The epidemiology of invasive candidiasis has evolved in recent years, warranting a review of the changes and the implications for current and future diagnosis and treatment. The overall burden of invasive candidiasis remains high, particularly in the expanding populations of patients at risk of opportunistic infection, such as the elderly or immunosuppressed. Progressive shifts from Candida albicans to non-albicans Candida spp. have been observed globally. The recent emergence of novel, multiresistant species, such as Candida auris, amplifies the call for vigilance in detection and advances in treatment. Among the current treatment options, fluconazole is still widely used throughout the world. Increased resistance to fluconazole, both acquired and naturally emerging, has been observed. Resistance to echinocandins is presently low but this may change with increased use. Improvement of diagnostic techniques and strategies, development of international surveillance networks and implementation of antifungal stewardship programmes represent major challenges for a better epidemiological control of invasive candidiasis.

Indexed as

Antifungal AgentsAntimicrobial StewardshipCandidaCandidiasis, InvasiveDrug Resistance, FungalEpidemiological MonitoringGlobal HealthHumansPrevalenceAntifungal Agents

Identifiers

PMID29304207
PMCPMC11931512
OpenAlexW2782394839

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.