ArticlePloS one2018
Occlusal force is correlated with cognitive function directly as well as indirectly via food intake in community-dwelling older Japanese: From the SONIC study.
Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
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Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it, 58 citations in OpenAlex.
- The predictive value of masticatory function for adverse health outcomes in older adults: a systematic review.The journal of nutrition, health & aging · 2024Pooled it
- Use of handgrip strength measurement as an alternative for assessing chewing function in people with dementia.BMC geriatrics · 2022Trial
- Chronic periodontitis and systemic inflammation in the elderly: implications for neurodegeneration.Journal of neuroinflammation · 2026Review
- Association of Oral Hypofunction with Reduced Hand Dexterity in Community-Dwelling Older Adults: A Cross-Sectional Study.Clinical interventions in aging · 2026Article
- Effects of dental prostheses and occlusal force on adverse health outcomes in community-dwelling older adults lacking functional dentition: The Longitudinal Study of the Tsurugaya Project.The journal of nutrition, health & aging · 2025Article
- Multidimensional insights about healthy aging from the cohort study for community-dwelling older adults: The SONIC study.Geriatrics & gerontology international · 2025Review
- Spatial and temporal dynamic changes of oral microbiome in removable partial denture wearers: a longitudinal study using full-length 16S rRNA sequencing.Journal of oral microbiology · 2025Article
- Predicting cognitive function changes from oral health status: a longitudinal cohort study.Scientific reports · 2024Article
- Search for unknown neural link between the masticatory and cognitive brain systems to clarify the involvement of its impairment in the pathogenesis of Alzheimer's disease.Frontiers in cellular neuroscience · 2024Review
- Risk factors of cognitive impairment: Impact of decline in oral function.The Japanese dental science review · 2023Review
- Associations of oral health status and swallowing function with cognitive impairment in the aging population: a cross-sectional study.BMC oral health · 2023Article
- Does the Loss of Teeth Have an Impact on Geriatric Patients' Cognitive Status?Journal of clinical medicine · 2023Article
- Assessment of subjective and objective masticatory function among elderly individuals with mild cognitive impairment.Aging clinical and experimental research · 2023Article
- Relationships between the Nutrition Status and Oral Measurements for Sarcopenia in Older Japanese Adults.Journal of clinical medicine · 2022Article
- Standard Values and Concurrent Validity of a Newly Developed Occlusal Force-Measuring Device among Community-Dwelling Older Adults: The Otassha Study.International journal of environmental research and public health · 2022Article
- The impact of tooth loss on cognitive function.Clinical oral investigations · 2022Article
- Capacitive-Type Pressure-Mapping Sensor for Measuring Bite Force.International journal of environmental research and public health · 2022Article
- Development of a system to analyze oral frailty associated with Alzheimer's disease using a mouse model.Frontiers in aging neuroscience · 2022Article
- Patients with mild cognitive impairment diagnosed at dementia clinic display decreased maximum occlusal force: a cross-sectional study.BMC oral health · 2021Article
- A cross-sectional study of relationships between periodontal disease and general health: The Hitachi Oral Healthcare Survey.BMC oral health · 2021Article
Corrections and comments
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Authors and funding
30 authors at 6 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundGrowing evidence suggests that oral health may be an important factor associated with cognitive function in aged populations. However, many previous studies on this topic used insensitive oral indicators or did not include certain essential covariates. Thus, we examined the association between occlusal force and cognitive function in a large sample of older adults, controlling for dietary intake, vascular risk factors, inflammatory biomarkers, depression, and genetic factors.
methodsIn this cross-sectional study of older community-dwelling Japanese adults, we examined data collected from 994 persons aged 70 years and 968 persons aged 80 years. Cognitive function was measured using the Japanese version of the Montreal Cognitive Assessment (MoCA-J). Oral status and function were evaluated according to the number of remaining teeth, periodontal pocket depth, and maximal occlusal force. Associations between MoCA-J scores and occlusal force were investigated via bivariate and multivariate analyses.
resultsEducation level, financial status, depression score, and intake of green and yellow vegetables, as well as number of teeth and occlusal force, were significantly correlated with MoCA-J scores in both age groups. Among individuals aged 80 years, CRP and periodontal status were weakly but significantly associated with MoCA-J score. After controlling for all significant variables via bivariate analyses, the correlation between maximal occlusal force and cognitive function persisted. A path analysis confirmed the hypothesis that cognitive function is associated with occlusal force directly as well as indirectly via food intake.
conclusionsAfter controlling for possible factors, maximal occlusal force was positively associated with cognitive function directly as well as indirectly through dietary intake.
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