ArticleOrganic letters2018
Heck Reaction of Electronically Diverse Tertiary Alkyl Halides.
Article in Organic letters, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.
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Who cites it
45 citing papers in PubMed.
- Ligand assisted Co(ii) catalyzed direct C-H alkylation of aryl ketones with diverse alkyl halides.Chemical science · 2026Article
- Palladium-Catalyzed Gem-Diborylalkylation of Silyl Enol Ethers and N-Vinylacetamide via Diboryl Carbon-Centered Radicals.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Synthesis of Borylated Orphaned Cyclopropanes through a Boron-Enabled Cycloisomerization Reaction.Journal of the American Chemical Society · 2025Article
- Photocatalysis Enables Chemodivergent Radical Polar Crossover: Ritter-Type Amidation vs Heck-Type Olefin Carbofunctionalizations.Chemistry (Weinheim an der Bergstrasse, Germany) · 2025Article
- Excited-State Palladium-Catalyzed Radical Allylic Alkylation: Rapid Access to C2-Allyl Carbohydrates.ACS catalysis · 2025Article
- Illuminating Palladium Catalysis.Accounts of chemical research · 2025Article
- α-Halocarbonyls as a Valuable Functionalized Tertiary Alkyl Source.ChemistryOpen · 2024Review
- General Regio- and Diastereoselective Allylic C-H Oxygenation of Internal Alkenes.Journal of the American Chemical Society · 2024Article
- Recent Advances in Visible Light Induced Palladium Catalysis.Angewandte Chemie (International ed. in English) · 2024Review
- Stereoselective Copper-Catalyzed Olefination of Imines.Angewandte Chemie (International ed. in English) · 2024Article
- One-Pot Formal Carboradiofluorination of Alkenes: A Toolkit for Positron Emission Tomography Imaging Probe Development.Journal of the American Chemical Society · 2023Article
- Merging of Light/Dark Palladium Catalytic Cycles Enables Multicomponent Tandem Alkyl Heck/Tsuji-Trost Homologative Amination Reaction toward Allylic Amines.Journal of the American Chemical Society · 2023Article
- Advances in Selected Heterocyclization Methods.Synlett : accounts and rapid communications in synthetic organic chemistry · 2023Article
- Enhanced Excited-State Hydricity of Pd-H Allows for Unusual Head-to-Tail Hydroalkenylation of Alkenes.Journal of the American Chemical Society · 2023Article
- Pd-Catalyzed Organometallic-Free Homologation of Arylboronic Acids Enabled by Chemoselective Transmetalation.ACS catalysis · 2023Article
- Aryl-to-alkyl radical relay Heck reaction of amides with vinyl arenes.Chemical science · 2023Article
- Palladium Hydride-Enabled Hydroalkenylation of Strained Molecules.Journal of the American Chemical Society · 2022Article
- Divergent regioselective Heck-type reaction of unactivated alkenes and N-fluoro-sulfonamides.Nature communications · 2022Article
- Excited-state palladium-catalysed reductive alkylation of imines: scope and mechanism.Chemical science · 2022Article
- A visible-light activated secondary phosphine oxide ligand enabling Pd-catalyzed radical cross-couplings.Nature communications · 2022Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
The efficient Pd-catalyzed Heck reaction of diverse tertiary alkyl halides with alkenes has been developed. Unactivated tertiary alkyl halides efficiently react at room temperature under visible light irradiation with no exogenous photosensitizers required. For activated tertiary alkyl halides, the same catalytic system works well without light. These methods offer a general access to electronically diverse alkenes possessing quaternary and functionalized tertiary allylic carbon centers. The substituents at these centers include alkyl-, carbalkoxy-, tosyl-, phosphonyl-, and boronate groups. It was also shown that the end-game mechanism of this transformation may vary depending on the type of the substrates used.
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Registered trials
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