Evidence map›Paper›PMID 29302777›Full record

SynthesisActa neuropathologica2018

Circumscribed/non-diffuse histology confers a better prognosis in H3K27M-mutant gliomas.

Drew Pratt, Siva Kumar Natarajan, Adam Banda, Caterina Giannini, Pankaj Vats, Carl Koschmann, Rajen Mody, Arul Chinnaiyan, Sriram Venneti

Abstract readLetterSystematic Review
In one paragraph

Synthesis in Acta neuropathologica, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Molecular features in gangliogliomas: a systematic review.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2026
    Pooled it
  2. Adult spinal cord diffuse midline gliomas with piloid features have a better prognosis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
    Article
  3. Article
  4. H3 K27M mutation in rosette-forming glioneuronal tumors: a potential diagnostic pitfall.Virchows Archiv : an international journal of pathology · 2025
    Article
  5. Molecular and Pathological Features of Paediatric High-Grade Gliomas.International journal of molecular sciences · 2024
    Review
  6. Article
  7. Review
  8. Review
  9. Review
  10. Frontal lobe mass in a 46-year-old woman.Brain pathology (Zurich, Switzerland) · 2024
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Drew PrattDepartment of Pathology, University of Michigan, Ann Arbor, MI, 48104, USA.
Siva Kumar NatarajanDepartment of Pathology, University of Michigan, Ann Arbor, MI, 48104, USA.
Adam BandaDepartment of Pathology, University of Michigan, Ann Arbor, MI, 48104, USA.
Caterina GianniniLaboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA.
Pankaj VatsMichigan Center for Translational Pathology, Ann Arbor, MI, USA.
Carl KoschmannDepartment of Pediatrics, University of Michigan School of Medicine, Ann Arbor, MI, USA.
Rajen ModyDepartment of Pediatrics, University of Michigan School of Medicine, Ann Arbor, MI, USA.
Arul ChinnaiyanMichigan Center for Translational Pathology, Ann Arbor, MI, USA.
Sriram VennetiDepartment of Pathology, University of Michigan, Ann Arbor, MI, 48104, USA. svenneti@med.umich.edu.

Funding

CELLULAR AND MOLECULAR BIOLOGY AT MICHIGANT32GM007315 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI PUTHENVEEDU, MANOJKUMAR A · 1985 to 2021
$12.8M
University of Michigan Postbaccalaureate Research Education Program (UM PREP)R25GM086262 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ALLEN, BENJAMIN · 2009 to 2024
$6.1M
Targeting ATRX-Deficient Pediatric GBMK08NS099427 · NINDS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI KOSCHMANN, CARL J · 2017 to 2021
$811k
Unraveling glutamine metabolism in gliomas by PET imaging and biochemical methodsK08CA181475 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI VENNETI, SRIRAM · 2014 to 2018
$701k
NCI NIH HHS K08 CA181475NIGMS NIH HHS R25 GM086262NIGMS NIH HHS T32 GM007315NINDS NIH HHS K08 NS099427
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Brain NeoplasmsGliomaHistonesHumansPrognosisSpinal Cord NeoplasmsSurvival AnalysisHistones

Identifiers

PMID29302777
PMCPMC6018022

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.