ArticleNPJ Regenerative medicine2016
Tissue- and time-directed electroporation of CAS9 protein-gRNA complexes
Article in NPJ Regenerative medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 36 citations in OpenAlex.
- Ependymoglial cells are critical for cortex regeneration in axolotls.Nature communications · 2026Article
- Optimized toolkit for the manipulation of immortalized axolotl fibroblasts.Methods (San Diego, Calif.) · 2025Article
- Sall4 regulates downstream patterning genes during limb regeneration.Developmental biology · 2024Article
- Tail and Spinal Cord Regeneration in Urodelean Amphibians.Life (Basel, Switzerland) · 2024Review
- A Practical Guide for CRISPR-Cas9-Induced Mutations in Axolotls.Methods in molecular biology (Clifton, N.J.) · 2023Article
- The use of transgenics in the laboratory axolotl.Developmental dynamics : an official publication of the American Association of Anatomists · 2022Review
- Regulation of stem cell identity by miR-200a during spinal cord regeneration.Development (Cambridge, England) · 2022Article
- CRISPR/Cas systems: Delivery and application in gene therapy.Frontiers in bioengineering and biotechnology · 2022Review
- The Axolotl's journey to the modern molecular era.Current topics in developmental biology · 2022Article
- EditingInternational journal of molecular sciences · 2021Review
- Spatiotemporal control of cell cycle acceleration during axolotl spinal cord regeneration.eLife · 2021Article
- Towards comparative analyses of salamander limb regeneration.Journal of experimental zoology. Part B, Molecular and developmental evolution · 2021Review
- Salamanders: The molecular basis of tissue regeneration and its relevance to human disease.Current topics in developmental biology · 2021Review
- Article
- A Comparative Perspective on Brain Regeneration in Amphibians and Teleost Fish.Developmental neurobiology · 2019Review
- Application and optimization of CRISPR-Cas9-mediated genome engineering in axolotl (Ambystoma mexicanum).Nature protocols · 2018Article
- A Regeneration Toolkit.Developmental cell · 2018Review
- Insights into Electroreceptor Development and Evolution from Molecular Comparisons with Hair Cells.Integrative and comparative biology · 2018Article
- Delivery strategies of the CRISPR-Cas9 gene-editing system for therapeutic applications.Journal of controlled release : official journal of the Controlled Release Society · 2017Review
- Efficient gene knockin in axolotl and its use to test the role of satellite cells in limb regeneration.Proceedings of the National Academy of Sciences of the United States of America · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A rapid method for temporally and spatially controlled CRISPR-mediated gene knockout in vertebrates will be an important tool to screen for genes involved in complex biological phenomena like regeneration. Here we show that
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.