Evidence map›Paper›PMID 29302315›Full record

ArticleJournal of global health2017

Association between internalized stigma and depression among HIV-positive persons entering into care in Southern India.

Brian T Chan, Amrose Pradeep, Lakshmi Prasad, Vinothini Murugesan, Ezhilarasi Chandrasekaran, Nagalingeswaran Kumarasamy, Kenneth H Mayer, Alexander C Tsai

Open access · goldAbstract read
In one paragraph

Article in Journal of global health, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Pooled it
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  9. Association between Internalized Stigma and Depression among People Living with HIV in Thailand.International journal of environmental research and public health · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Brian T ChanDivision of Infectious Diseases, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Amrose PradeepY. R. Gaitonde Centre for AIDS Research and Education, Chennai, India.
Lakshmi PrasadY. R. Gaitonde Centre for AIDS Research and Education, Chennai, India.
Vinothini MurugesanY. R. Gaitonde Centre for AIDS Research and Education, Chennai, India.
Ezhilarasi ChandrasekaranY. R. Gaitonde Centre for AIDS Research and Education, Chennai, India.
Nagalingeswaran KumarasamyY. R. Gaitonde Centre for AIDS Research and Education, Chennai, India.
Kenneth H MayerHarvard Medical School, Boston, Massachusetts, USA.
Alexander C TsaiHarvard Medical School, Boston, Massachusetts, USA.
YR Gaitonde Centre for AIDS Research and Education · INBrigham and Women's Hospital · USFenway Health · USMGH Institute of Health Professions · US

Funding

The impact of HIV viral diversity and cellular immunity on HIV pathogenesisP30AI060354 · NIAID · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI RAJESH T GANDHI · 2004 to 2026
$94.4M
Harvard Clinical and Translational Science CenterKL2TR001100 · NCATS · HARVARD MEDICAL SCHOOL · PI NADLER, LEE MARSHALL · 2013 to 2017
$8.5M
Microenterprise to empower and improve health of HIV+ women in UgandaK23MH096620 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · PI TSAI, ALEXANDER C · 2012 to 2016
$922k
Syndemics and Loss From the HIV Care Continuum in IndiaK23MH110338 · NIMH · BRIGHAM AND WOMEN'S HOSPITAL · PI CHAN, BRIAN TAN · 2017 to 2020
$783k
NCATS NIH HHS KL2 TR001100NIAID NIH HHS P30 AI060354NIMH NIH HHS K23 MH096620NIMH NIH HHS K23 MH110338
6 · The paper itself

Abstract

backgroundIn India, which has the third largest HIV epidemic in the world, depression and HIV-related stigma may contribute to high rates of poor HIV-related outcomes such as loss to care and lack of virologic suppression.

methodsWe analyzed data from a large HIV treatment center in southern India to estimate the burden of depressive symptoms and internalized stigma among Indian people living with HIV (PLHIV) entering into HIV care and to test the hypothesis that probable depression was associated with internalized stigma. We fitted modified Poisson regression models, adjusted for sociodemographic variables, with probable depression (PHQ-9 score ≥10 or recent suicidal thoughts) as the outcome variable and the Internalized AIDS-Related Stigma Scale (IARSS) score as the explanatory variable.

findings521 persons (304 men and 217 women) entering into HIV care between January 2015 and May 2016 were included in the analyses. The prevalence of probable depression was 10% and the mean IARSS score was 2.4 (out of 6), with 82% of participants endorsing at least one item on the IARSS. There was a nearly two times higher risk of probable depression for every additional point on the IARSS score (Adjusted Risk Ratio: 1.83; 95% confidence interval, 1.56-2.14).

conclusionsDepression and internalized stigma are highly correlated among PLHIV entering into HIV care in southern India and may provide targets for policymakers seeking to improve HIV-related outcomes in India.

Indexed as

Internal-External ControlStereotypingAdultCross-Sectional StudiesDepressionFemaleHIV InfectionsHumansIndiaMaleMiddle AgedSurveys and QuestionnairesTreatment Outcome

Identifiers

PMID29302315
PMCPMC5735782
OpenAlexW2774294942

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.