ArticlePatient preference and adherence2018
Risks versus benefits of medication use during pregnancy: what do women perceive?
Article in Patient preference and adherence, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Congenital anomalies and risk factors in Africa: a systematic review and meta-analysis.BMJ paediatrics open · 2023Pooled it
- Development of a novel adherence scale for antidepressants in pregnancy: Results from a cross-sectional study.Exploratory research in clinical and social pharmacy · 2026Article
- Determinants of off-label drug acceptance in pregnancy: insights from an extended UTAUT model.Frontiers in pharmacology · 2026Article
- Parental Socioeconomic, Demographic, and Neonatal Factors Influencing Infants' Low Birth Weight: A Cross-Sectional Study in Bangladesh.Health science reports · 2025Article
- Knowledge, Attitude, and Practice Toward Medication Use During Pregnancy: A Hospital-Based Cross-Sectional Survey.Journal of obstetrics and gynaecology of India · 2025Article
- Medication use from conception to the first antenatal appointment: agreement between maternal self-report to midwife and prescribing records in Northern Ireland in 2011-2016.International journal of population data science · 2025Article
- Prevalence and association of self-medication practices with personal and educational factors among university employees of Saudi Arabia: A cross-sectional study.Journal of family medicine and primary care · 2024Article
- Prevalence of Self-Medication Practice and Associated Factors among Pregnant Women Who Attended Antenatal Care at Public Hospitals of North Shewa Zone, Amhara Region, Ethiopia.Advances in pharmacological and pharmaceutical sciences · 2024Article
- A cross-sectional study on the knowledge, attitude, and practice of pregnant women regarding medication use and restriction during pregnancy.Exploratory research in clinical and social pharmacy · 2023Article
- Self-medication practices among pregnant women in Ethiopia.Journal of pharmaceutical policy and practice · 2023Article
- Medication Use and Associated Factors Among Indonesian Pregnant Women: A Cross-Sectional Study.Journal of multidisciplinary healthcare · 2023Article
- Identifying target areas of medicines information efforts to pregnant and breastfeeding women by reviewing questions to SafeMotherMedicine: A Norwegian web-based public medicines information service.BMC pregnancy and childbirth · 2022Article
- Women's Perceptions of Medication Use During Pregnancy and Breastfeeding in Saudi Arabia.Cureus · 2022Article
- A descriptive analysis of calls to the NSW Teratogen Information Service regarding use of anti-infectives during pregnancy.PloS one · 2022Article
- Prevalence, determinants and attitude towards herbal medicine use in the first trimester of pregnancy in Cameroon: A survey in 20 hospitals.PLOS global public health · 2022Article
- Dutch trends in the use of potentially harmful medication during pregnancy.British journal of clinical pharmacology · 2020Article
- SafeMotherMedicine: Aiming to Increase Women's Empowerment in Use of Medications During Pregnancy and Breastfeeding.Maternal and child health journal · 2020Article
- Maternal use of drugs and preeclampsia.British journal of clinical pharmacology · 2019Article
- Perceptions of medicine use among pregnant women: an interview-based study.International journal of clinical pharmacy · 2019Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundUnderstanding perception of risks and benefits is essential for informed patient choices regarding medical care. The primary aim of this study was to evaluate the perception of risks and benefits of 9 drug classes during pregnancy and associations with women's characteristics.
methodsQuestionnaires were distributed to pregnant women who attended a Dutch Obstetric Care facility (first- and second-line care). Mean perceived risk and benefit scores were computed for 9 different drug classes (paracetamol, antacids, antibiotics, antifungal medication, drugs against nausea and vomiting, histamine-2 receptor antagonists/proton pump inhibitors, antidepressants, nonsteroidal anti-inflammatory drugs, and sedatives/anxiolytics). For each participant, we computed weighted risk and benefit sum scores with principal component analysis. In addition, major concerns regarding medication use were evaluated.
resultsThe questionnaire was completed by 136 women (response rate 77%). Pregnant women were most concerned about having a child with a birth defect (35%), a miscarriage (35%), or their child developing an allergic disease (23%), respectively, as a result of drug use. The majority of studied drug classes were perceived relatively low in risk and high in benefit. Higher risk scores were reported if women were in their first trimesters of pregnancy (
conclusionPregnant women's concerns regarding potential drug adverse effects were not only focused on congenital birth defects but also included a wider range of adverse outcomes. This study showed that most of the studied drug classes were perceived relatively low in risk and high in benefit.
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