Evidence map›Paper›PMID 29301956›Full record

ArticlePlant physiology2018

Genome-Wide Analysis of the Arabidopsis Replication Timing Program.

Lorenzo Concia, Ashley M Brooks, Emily Wheeler, Gregory J Zynda, Emily E Wear, Chantal LeBlanc, Jawon Song, Tae-Jin Lee, Pete E Pascuzzi, Robert A Martienssen and 3 more

Abstract read
In one paragraph

Article in Plant physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed.

  1. Article
  2. Article
  3. Organization principles of dynamic three-dimensional genome architecture associated with centromere clustering states.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  4. Nanorate sequencing reveals theProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Enhancers associated with unstable RNAs are rare in plants.bioRxiv : the preprint server for biology · 2023
    Article
  17. Article
  18. Crossover patterning in plants.Plant reproduction · 2023
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Lorenzo ConciaDepartment of Plant and Microbial Biology, North Carolina State University, Raleigh, North Carolina 27695.ORCID 0000-0002-7401-7214
Ashley M BrooksDepartment of Plant and Microbial Biology, North Carolina State University, Raleigh, North Carolina 27695.
Emily WheelerDepartment of Plant and Microbial Biology, North Carolina State University, Raleigh, North Carolina 27695.
Gregory J ZyndaTexas Advanced Computing Center, University of Texas at Austin, Austin, Texas 78758.ORCID 0000-0003-4992-9614
Emily E WearDepartment of Plant and Microbial Biology, North Carolina State University, Raleigh, North Carolina 27695.ORCID 0000-0003-2002-6980
Chantal LeBlancHoward Hughes Medical Institute, Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724.
Jawon SongTexas Advanced Computing Center, University of Texas at Austin, Austin, Texas 78758.ORCID 0000-0002-9916-3816
Tae-Jin LeeDepartment of Plant and Microbial Biology, North Carolina State University, Raleigh, North Carolina 27695.
Pete E PascuzziPurdue University Libraries, Purdue University, West Lafayette, Indiana 47907.ORCID 0000-0002-9316-4404
Robert A MartienssenHoward Hughes Medical Institute, Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724.
Matthew W VaughnTexas Advanced Computing Center, University of Texas at Austin, Austin, Texas 78758.ORCID 0000-0002-1384-4283
William F ThompsonDepartment of Plant and Microbial Biology, North Carolina State University, Raleigh, North Carolina 27695.
Linda Hanley-BowdoinDepartment of Plant and Microbial Biology, North Carolina State University, Raleigh, North Carolina 27695 linda_hanley-bowdoin@ncsu.edu.ORCID 0000-0001-7999-8595

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Eukaryotes use a temporally regulated process, known as the replication timing program, to ensure that their genomes are fully and accurately duplicated during S phase. Replication timing programs are predictive of genomic features and activity and are considered to be functional readouts of chromatin organization. Although replication timing programs have been described for yeast and animal systems, much less is known about the temporal regulation of plant DNA replication or its relationship to genome sequence and chromatin structure. We used the thymidine analog, 5-ethynyl-2'-deoxyuridine, in combination with flow sorting and Repli-Seq to describe, at high-resolution, the genome-wide replication timing program for Arabidopsis (

Indexed as

Chromosomes, PlantDNA Replication TimingArabidopsisChromatinDNA Transposable ElementsFlow CytometryGenome, PlantGenome-Wide Association StudySequence Analysis, DNAS PhaseChromatinDNA Transposable Elements

Identifiers

PMID29301956
PMCPMC5841712

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.