Evidence map›Paper›PMID 29301955›Full record

ArticlePlant physiology2018

The Cytokinin Oxidase/Dehydrogenase CKX1 Is a Membrane-Bound Protein Requiring Homooligomerization in the Endoplasmic Reticulum for Its Cellular Activity.

Michael C E Niemann, Henriette Weber, Tomáš Hluska, Georgeta Leonte, Samantha M Anderson, Ondřej Novák, Alessandro Senes, Tomáš Werner

Open access · bronzeAbstract read
In one paragraph

Article in Plant physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
10.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 55 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Analysis of Protein Glycosylation in the ER.Methods in molecular biology (Clifton, N.J.) · 2024
    Article
  8. Review
  9. Article
  10. Cloning of Three Cytokinin Oxidase/Dehydrogenase Genes inCurrent issues in molecular biology · 2023
    Article
  11. Article
  12. Review
  13. Genotype-independent plant transformation.Horticulture research · 2022
    Article
  14. Evolution of the Cytokinin Dehydrogenase (CKX) Domain.Journal of molecular evolution · 2021
    Article
  15. Article
  16. Article
  17. Review
  18. The soybean (Plant direct · 2021
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 4 countries.

Michael C E NiemannInstitute of Biology/Applied Genetics, Dahlem Centre of Plant Sciences, Freie Universität Berlin, D-14195 Berlin, Germany.
Henriette WeberInstitute of Biology/Applied Genetics, Dahlem Centre of Plant Sciences, Freie Universität Berlin, D-14195 Berlin, Germany.
Tomáš HluskaDepartment of Molecular Biology, Centre of the Region Haná for Biotechnological and Agricultural Research, Palacký University, 78371 Olomouc, Czech Republic.ORCID 0000-0002-1854-3949
Georgeta LeonteInstitute of Biology/Applied Genetics, Dahlem Centre of Plant Sciences, Freie Universität Berlin, D-14195 Berlin, Germany.
Samantha M AndersonDepartment of Biochemistry, University of Wisconsin, Madison, Wisconsin 53706.ORCID 0000-0001-6114-0427
Ondřej NovákLaboratory of Growth Regulators, Centre of the Region Haná for Biotechnological and Agricultural Research, Palacký University and Institute of Experimental Botany ASCR, 78371 Olomouc, Czech Republic.ORCID 0000-0003-3452-0154
Alessandro SenesDepartment of Biochemistry, University of Wisconsin, Madison, Wisconsin 53706.ORCID 0000-0002-3807-2275
Tomáš WernerInstitute of Biology/Applied Genetics, Dahlem Centre of Plant Sciences, Freie Universität Berlin, D-14195 Berlin, Germany tomas.werner@uni-graz.at.ORCID 0000-0001-5179-0581
Freie Universität Berlin · DEUniversity of Wisconsin–Madison · USCzech Academy of Sciences, Biology Centre · CZCzech Academy of Sciences, Institute of Experimental Botany · CZUniversity of Graz · AT

Funding

Research Training for Computation and Informatics in Biology and MedicineT15LM007359 · NLM · UNIVERSITY OF WISCONSIN-MADISON · PI Mark W. Craven, Colin Noel Dewey · 2002 to 2026
$22.6M
Identify and characterize genes involved in X-chromosome inactivationR01GM099722 · NIGMS · MAYO CLINIC ROCHESTER · PI ZHANG, ZHIGUO · 2012 to 2015
$1.2M
NIGMS NIH HHS R01 GM099722NLM NIH HHS T15 LM007359
6 · The paper itself

Abstract

Degradation of the plant hormone cytokinin is controlled by cytokinin oxidase/dehydrogenase (CKX) enzymes. The molecular and cellular behavior of these proteins is still largely unknown. In this study, we show that CKX1 is a type II single-pass membrane protein that localizes predominantly to the endoplasmic reticulum (ER) in Arabidopsis (

Indexed as

Protein MultimerizationAmino Acid SequenceArabidopsisArabidopsis ProteinsEndoplasmic ReticulumGreen Fluorescent ProteinsMembrane ProteinsOxidoreductasesProtein DomainsProtein Sorting SignalsProtein StabilityRecombinant Fusion ProteinsArabidopsis Proteinscytokinin oxidaseGreen Fluorescent ProteinsMembrane ProteinsOxidoreductasesProtein Sorting SignalsRecombinant Fusion Proteins

Identifiers

PMID29301955
PMCPMC5841711
OpenAlexW2781589994

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.