Evidence map›Paper›PMID 29301946›Full record

ReviewGenetics2018

Advances in Engineering the Fly Genome with the CRISPR-Cas System.

Ethan Bier, Melissa M Harrison, Kate M O'Connor-Giles, Jill Wildonger

Open access · bronzeAbstract readReview
In one paragraph

Review in Genetics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 93 papers.

0numbers the graph read from it
0cells of the map it votes in
93citing papers in PubMed
9.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

93 citing papers in PubMed, 175 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Studying Cellular Senescence Using the Model Organism Drosophila melanogaster.Methods in molecular biology (Clifton, N.J.) · 2025
    Article
  13. Diversity ofFrontiers in cell and developmental biology · 2025
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Characterizing the Protein Isoforms ofInternational journal of molecular sciences · 2023
    Article
  19. Experimental models for ageing research.Histology and histopathology · 2023
    Review
  20. CRISPR/Cas9-mediated knock-in inGene and genome editing · 2023
    Article

33 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Ethan BierCell and Developmental Biology, University of California, San Diego, La Jolla, California 92093-0349 ebier@ucsd.edu mharrison3@wisc.edu oconnorgiles@wisc.edu wildonger@wisc.edu.
Melissa M HarrisonDepartment of Biomolecular Chemistry, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin 53706 ebier@ucsd.edu mharrison3@wisc.edu oconnorgiles@wisc.edu wildonger@wisc.edu.ORCID 0000-0002-8228-6836
Kate M O'Connor-GilesLaboratory of Genetics and Laboratory of Cell and Molecular Biology, Wisconsin 53706 ebier@ucsd.edu mharrison3@wisc.edu oconnorgiles@wisc.edu wildonger@wisc.edu.ORCID 0000-0002-2259-8408
Jill WildongerBiochemistry Department, University of Wisconsin-Madison, Wisconsin 53706 ebier@ucsd.edu mharrison3@wisc.edu oconnorgiles@wisc.edu wildonger@wisc.edu.ORCID 0000-0002-6462-5830
University of Wisconsin–Madison · USUniversity of California, San Diego · US

Funding

The mutagenic chain reaction: a method for autocatalyic gene disseminationR01GM117321 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BIER, ETHAN · 2016 to 2024
$2.5M
MOLECULAR MOTORS AND NEURONAL MICROTUBULE POLARITYR01NS102385 · NINDS · UNIVERSITY OF WISCONSIN-MADISON · PI WILDONGER, JILL C · 2017 to 2022
$1.6M
Mechanisms of genomic reprogramming and transcriptional activation in the embryoR01GM111694 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI HARRISON, MELISSA · 2015 to 2019
$1.6M
NIGMS NIH HHS R01 GM111694NIGMS NIH HHS R01 GM117321NINDS NIH HHS R01 NS102385
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

CRISPR-Cas SystemsGenetic EngineeringGenomeAnimalsBacteriaDNA RepairDrosophilaGene EditingGene TargetingGenomicsRNA, Guide, CRISPR-Cas SystemsRNA, Guide, CRISPR-Cas SystemsCRISPR-CasDrosophilaFlyBookgene drivegene editinggenome engineering

Identifiers

PMID29301946
PMCPMC5753851
OpenAlexW2781902192

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.